“a clear trend”

23 Age is a well-established independent risk factor for the development of BCa, with a clear trend showing that individuals aged 65 and older have a higher incidence of cancer and associated mortality compared to those under 65.

9 With all cell lines, a clear trend can be observed in which Cab FT was more potent at lower concentrations (between 2.5–0.3125 μg/mL) compared with Cab ( Figure 1 A).

Overall, there was a higher abundance of fungal species in the RGS samples and a clear trend of decreasing fungal community diversity with increasing altitude, based on the Unifrac distances. 3.

Their findings indicated that the use of surgery, chemotherapy, and tumor location in the anterior mediastinum was associated with a clear trend toward improved survival.

There is a clear trend in the literature showing that KRAS plays the important role of predicting early checkpoint of transition from hyperplastic endometrium to early-stage well-differentiated (grade I) estrogen-related EC, as well as further transition from low- to high-grade type I EC ( 44 - 46 ).

Fourth, there is a clear trend toward increasing interdisciplinary collaboration in this field.

There was a clear trend between lower socioeconomic status and increased mortality but less pronounced with incidence.

Although the overall effect of the metabolism of the six OPPs on OA prevalence was not statistically significant when all OPPs metabolites were above their 50th percentile, there was still a clear trend toward an increase.

In the above-mentioned study on glucagon counterregulation during hypoglycemia, vildagliptin treatment enhanced the hypoglycemia-induced inhibition of insulin secretion and there was a clear trend by vildagliptin to increase the activity of the autonomic nervous system as indirectly observed by measuring the marker pancreatic polypeptide. 34 Therefore, several mechanisms may explain the protective effect of vildagliptin on glucagon counterregulation.

Although there was no significant decrease in the cell viability of si-ACAA2 stimulated by IS, there was a clear trend ( Figure 3 f).

We varied injection amounts of a metabolite extract derived from MCF7 cells by using different split ratios, and observed a clear trend of the number of metabolites identified as a function of gradient length and sample amount ( Fig. 4 ).

Nevertheless, the lack of a clear trend in changes of Cd concentration in fraction G over the exposure time makes the meaning of this interaction questionable and difficult to interpret.

A clear trend for a transmittance reduction with increasing acoustic stimulus frequency is observed for all compositions.

The quartile analysis further strengthened this conclusion, revealing a clear trend of increasing T2DM risk across higher FF-LL categories.

On size and connections It is generally accepted as a clear trend in mammalian brain evolution that greater brain size is correlated with an increase in the number of distinct cortical areas (Campos and Welker, 1976 ; Kaas, 1987 ) and increased cortical folding.

When compared with a historical series, the 20G PC showed a clear trend toward better performance.

2B , the compound 7-(phenylcarbamate)-3,4-dihydrocadalene did not show a clear trend of MCF7 cell viability reduction dependently on the concentration or the time.

Therefore, in Figure 6 B, we analyze the influence of percentage of C sp 2 on the CO 2 uptake. The results in Figure 6 B do not show a clear trend between these two parameters.

The resulting MRDs followed a clear trend, Fig. 4 (d).

[31] Comparing the reactivity of the oxygen‐bridged 2 towards CO 2 with that of the methylene‐bridged systems t Bu 2 P−CH 2 −E(C 2 F 5 ) 3 (E=Si, Sn), a clear trend can be observed.

However, HEK CC HHV-6A positivity was only slightly reduced by the receptor antagonist ( Figures 1G, H ) and viral DNA and RNA expression, although presenting a clear trend toward reduction (~20%) were not significantly affected ( Figures 1G, H ).

2 (a) and (b), which illustrate a clear trend of decreasing chlorophyll content with increasing HCHT time and relative humidity (RH).

The search suggests a clear trend toward the use of agro‐industrial residues and by‐products, which represent the largest category (46.3%).

Figure 3 does not show a clear trend on the impact of the origin of MSCs (autologous vs allogeneic) on the efficacy of intervention.

Among native-born and immigrant workers, we found a clear trend: the larger the company, the higher the IR across all years (Supplementary Table 7a, 7b, and 7c).