“a clear trend”

10.1136/esmoopen-2019-000656.supp1 Supplementary data Effectiveness in patients aged ≥75 years according to ECOG PS There was a clear trend towards improved PFS according to ECOG PS ( figure 2A ).

Specifically, there was a clear trend toward the downregulation of related genes, including Cyp2c9 , Cyp3a4 , Ugt1a1 and Ugt2a1 , in PA-treated cells.

Even though these results did not withstand a correction of multiple comparison, a clear trend was visible.

White and colleagues [ 30 ], who investigated a multicomponent, nurse-delivered family support intervention (FOUR SUPPORT) for the same target group, did not identify a clear trend.

A clear trend emerging from these studies is a rapid transition in livestock genetic improvement: from selection based purely on observable traits to decisions informed by an animal’s genetic makeup.

Data on prevalence in the community setting was only available from 2007 and unlike its hospital setting counterpart it did not suggest a clear trend.

Table 3 shows the mean CD4% and CD4 cell count of all children as well as in the subsets with either underweight or stunting, with a clear trend towards lower cell count and percentage among children above the age of 10 years in all three groups.

There was a clear trend that the frequency of lymph node metastases was associated with a larger micropapillary component.

Regarding dietary omega-3 intake, the analysis indicated a clear trend where higher quartiles of omega-3 intake were associated with lower odds of type 2 diabetes, supporting the hypothesis of a protective effect (P for trend: <0.001).

The substitution of fluoride in the lattice is characterized by a contraction of the a lattice parameter, as electronegative fluoride are expected to interact with surrounding calcium ions and occupy a position at their center, slightly offset from the position of native hydroxyl ions [ 25 , 38 , 39 , 40 ], while the evolution of the c length does not follow a clear trend.

However, a clear trend in the opinions of those with ESL about whether too much (as reported by 21% of ESL respondents) or too little text (as reported by 27% of ESL respondents) existed was not evident.

Logistic regression reveals a clear trend for an increasing proportion of anti-conservative histograms, starting from <10% in 2010 and surpassing 30% in 2020 ( S2 Fig ).

Regarding the use of data augmentation techniques, the results indicate that its use does not show a clear trend of improvement or deterioration in accuracy.

However, there is a clear trend between 675 and 710 °C of the peaks shifting to a higher 2θ, which indicates a contraction of the lattice.

Introduction It is remarkable that although environmental research and protection efforts as well as health-related investments are constantly increasing, the current world witnesses the significant increase of neurodegenerative and cardiovascular diseases, allergies, cancers and also a clear trend towards drastic deterioration of natural ecosystems.

To explore relationships among PIADS subscales, as a clear trend between two of the three dimensions was observed, Spearman’s Rho correlations were calculated to measure the strength and direction of associations.

Overall, a clear trend that indicated lower relative abundances of ASVs identified as Mortierella (ASV5, ASV6, ASV7, and ASV8) in ARD_C compared to Grass_C was observed.

Inclusion of a greater number of studies in pediatric patients could have shown improvement in glycemic control since there is still a clear trend to lower HbA1c by psychological intervention according to our subgroup analysis.

The results in children confirmed the results in the whole cohort, with statistically significant differences in all comparisons except for IgG against highly immunogenic antigens such as AMA1, EBA175, and MSP1 42 , where after adjusting for multiple comparisons statistical significance disappeared, although a clear trend remained (Fig.

Though autoantibody titer data have not been released from remibrutinib trials, data from trials with the highly-selective, noncovalent BTKi fenebrutinib (Genentech) indicate a clear trend.

In fact, all respiration-related parameters, including maximal respiration and non-mitochondrial oxygen consumption, showed a clear trend of diminishing in CERKL -deficient cells ( Figure 5 B–G).

Only IH 31% (8/26) was able to predict long-term response 38%, p < 0.02 (10/26), although there was a clear trend that those with clinical relapse were more likely not to achieve either ER or TR.

When viewed alongside the Gleason score patterns from Table 1 , a clear trend emerges for certain groups.

They found a clear trend that ring diameter shortened as age increased.

The specific heat per site shows minimal size dependence for the Zeeman interaction but displays a clear trend for the exchange and dipolar terms: the temperature at which the specific heat reaches its maximum increases with system size, signaling enhanced cooperative effects and a shift toward bulk-like behavior.