“a clear trend”

The starting dose of 30 μg/kg every 4 weeks was selected because a clear trend of REG3A upregulation at this level was observed in the phase 1a trial.

Over the past decade, a clear trend has emerged toward designing large, more highly sulfated structures, which generally exhibit enhanced anticoagulant activity.

Dynamic mechanical analysis reveals a clear trend of increasing storage modulus and T g with higher GC levels, signifying enhanced cross-link density and a more rigid polymer network.

The results of the present review appear as slightly contradicting across different disorders, but with a clear trend showing that the two conditions frequently coexist.

1 a) Significant differences were also shown between well- and moderately differentiated HSAs versus hemangiomas and there was a clear trend between well and moderately differentiated HSAs (Fig. 1 b).

Low numbers in each group also precluded a formal statistical analysis of the relationship between RF/ISG induction and tissue-specific viral load, although there was a clear trend towards upregulation coincident with high levels of CA-RNA in different LT.

The variable weight value (VIP) obtained according to the OPLS-DA model could effectively estimate the groups and show a clear trend of being separated in the context of positive and negative ions.

These advances highlight a clear trend toward intelligent and conformal integrated EM platforms; in this context, compact front-end SI suppression for co-located TX/RX full-duplex JCAS remains a key enabling functionality that is addressed in this work.

Sequence-logo analysis of each cluster highlights a clear trend in phospho-site sequence characteristics.

Regarding UDVA, a clear trend of gradual decline was found across the surveyed grade levels.

Moreover, the elongation at break of the samples in each diameter interval did not show a clear trend.

Furthermore, RecC is a component of exonuclease V, showing a clear trend in deletion strains sensitized to (fluoro)quinolones.

Although theoretical estimates suggest a clear trend in affinity, accurate experimental determination of K d values remains essential for quantitative validation.

Overall, in both comparisons, with respect to the CTRL and to the T0 microbiota, the LimpiAL treatment revealed a clear trend of implementing the microbial diversity.

δ 13 C shows that most of the dry dog food fell in an iso-space constrained by beef, grains, maize, and poultry, but with a clear trend to be clustered between poultry and maize ingredients ( Fig. 1A ).

The amino acidic profile was altered by the treatment, even though a clear trend could not be identified: lysine, isoleucine, valine, and phenylalanine degradation products could be identified among differential metabolites, together with tryptophan, arginine, methionine, and histidine precursors.

A clear trend was observed in which the EC 50 values decreased with decreasing molecular weight, indicating enhanced antioxidant activity in the lower-molecular-weight peptide fractions.

The results obtained when comparing the color intensity in the blue channel showed a clear trend toward a decrease in color for amplifications with higher RNA concentration.

In the premenopausal setting, risk, indication for chemotherapy and implementation of endocrine therapy therefore influence each other. With regard to the length of endocrine therapy, there is a clear trend among SG panellists to consider that the length of therapy is dependent on stage ( Fig. 3 , Questions 74 to 77 ).

Sisal, jute, and coir fibers exhibited a clear trend of decreasing composite strength as the fiber length was increased from 20 mm to 60 mm.

The ITO/2/Al memory device exhibited a clear trend: both SET and RESET voltages increased with decreasing temperature, which is characteristic of donor–acceptor-based systems due to reduced thermal activation and slower charge transfer dynamics.

Longitudinal data demonstrate a clear trend towards increasing incidence of youth-onset T2D globally over recent decades [ 1 , 18 ].

In initial analyzes, predefined electrocardiographic criteria exhibited a clear trend allowing differential diagnosis of TTC (data not shown).

It may be because the material properties do not show a clear trend, as they depend heavily on material type, impurity concentration, and manufacturing process. 31 In addition, the manufacturers only provide output data, such as matched-load output power, current, voltage, conversion efficiency, and open-circuit voltage, while structural dimensions and interior properties are unavailable.

However, their study demonstrated a clear trend toward decreased efficacy with later lines of treatment, which was not evident in our cohort when first-line versus subsequent-line therapy was compared [ 23 ].