“a clear trend”

In younger patients, the presence of the T280M mutation is associated with an increased risk of progressing to dialysis, with a clear trend observed across all eGFR stages, even at the highest filtration values.

49 The evolution of design guidelines illustrates a dynamic policy environment and highlights a clear trend towards more comprehensive design guidance.

Specific leaf weight (SLW), the dry weight of a leaf divided by its area, does show a clear trend with blue light significantly increasing SLW.

The data extracted from 91 peer-reviewed articles reveal a clear trend: IHC has become indispensable in the accurate identification and subclassification of SCC, particularly in cases with ambiguous histology or poorly differentiated features. 4.1.

Three exceptions to this observation were noted: (1) MP was consistently less accurate than the other methods but otherwise did not show a clear trend of change as dataset size increased, (2) MLE, MLE-length, MPL, and SNaQ’s topological accuracy decreased as dataset size increased from 6 to 7 taxa, and (3) SNaQ’s topological accuracy decreased as dataset size increased from 20 to 25 taxa.

Performance across depths The 100 m model shows a clear trend of increasing TSS with deeper water compared to the 20 m models based on the testing partition, although results were variable across regions ( Fig 6A ).

3 show a clear trend towards the appreciation of practical and organizational elements in coach education, highlighting these areas as particularly impactful in the coaches' professional development.

Table 1 shows the preferred method for scaling up mental health services and filling the mental health worker gap in Sudan so that most regions and districts would have the appropriate mental health personnel. Discussion This study showed a clear trend, which was consistent with other evidence of a ‘brain drain’ of psychiatrists from low-income countries.

For most morphological profiles, there is a clear trend for the sensitivity index to decrease with the auditory distances.

Overall, it is possible to observe a clear trend of better air quality indexes along the years, with the index “Good” increasing from 150 days per year in 2004 to more than 250 days per year in 2012.

Although the PRF-mediated differences in the gene expression of caspase 8 are generally not significant due to high standard deviations, a clear trend in caspase 8 gene expression in response to PRF treatment can be detected.

This analysis showed a clear trend that CRC tissues with low KCTD9 expression had higher β-catenin expression while the converse was true for CRC tissues with high KCTD9 expression (Fig. 7F ).

6 , according to the Cox model, there was a clear trend toward a progressive reduction of the adjusted risk of composite outcome as adherence with drug therapy increased, i.e., compared with low adherence, patients with intermediate and high adherence showed an adjusted risk reduction of 41% (95% CI, − 6 to 67%) and 55% (20–75%), respectively.

However, as the interaction between the expression of these molecules did not present a clear trend, further conclusions could not be drawn.

Although the presence of the 3 investigated lipid classes changed with the growth phases, it was not possible to identify a clear trend between the occurrence of each lipid class and the different growth phase and no apparent connection was found between the changes in growth phase and the increasing and decreasing DEL:TEL ratios.

Although, the H1 did not show significant differences when compared the V, there was a clear trend towards reducing SBP, and it is likely that a longer supplementation period could have achieved significant results. 3.6.

However, as expected, there was a clear trend of increased PUR measurements with decreasing global DNA methylation levels for all unmethylated repetitive element reactions.

We observe a clear trend indicating a gradual increase in length (Fig. 3A, B ).

The occurrence of EM displays a clear trend of familial aggregation, with the offspring of an EM mother having 3–9 fold higher risk of suffering the disease ( Kim et al., 2021 ).

Moreover, the improvement in debris, plaque, and gingival scores in the treatment group reflected a clear trend toward normalization, closely approaching values observed in healthy control cats.

Comparison with N trends in larger rivers and lakes in the same region The decreasing NO 3 trends in the easternmost catchments and absence of a clear trend in Øygardsbekken are consistent with long-term data from large rivers (Kaste et al. 2018 ; Norwegian Environment Agency 2018 ) and small lakes (Garmo and Skancke 2019 ) covering the same gradient in southern Norway (Figs. 5 a, 6 a).

According to the Lorenz curve of the distribution of agritainment resorts in each province ( Fig 4 ), it can be seen that there is a clear trend of a concave, indicating that the distribution of agritainment is particularly uneven in the following provinces and regions: Sichuan, Yunnan, Zhejiang, Guangdong, Jiangsu, and Guangxi.

A clear trend emerged in all the studies that included a squat jump (SJ) and a countermovement jump (CMJ) (i.e., the intervention groups), independent of training order, for participants who were not exposed to any type of high-intensity plyometric activity (including speed work).

There was a clear trend where 3.39 e − per pixel per second produced a substantial depression of the power at NPS(0).

The results of the present review appear as slightly contradicting across different disorders, but with a clear trend showing that the two conditions frequently coexist.