Barely Significant
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“a clear trend”

19,461 sentences · 19,461 papers · 31,348 search hits before verification · confirmed specimen

Sighted at

p<0.09

Listed by Hankins (2013) · Otte et al. (2022)

In the literature

On the other hand, while the T-type Ca 2+ channels blocker significantly improved pDab1 levels in F2688-1 NPCs, there is still a clear trend towards diminished expression of pDAB1 in these cells compared to untreated control cells (Fig. 3B ), corroborating our previous findings indicating that the variants in the RELN gene contribute to defective levels of this key regulator of Reelin signaling [ 14 ].
In the present study, we did not use a dose of 50 mg/kg/day, but we have established a LOAEL of 100 mg/kg/day for fetal end points and a NOAEL of 20 mg/kg/day, although there does appear to be a clear trend towards effects on the occurrence of MNGs at a dose of 20 mg/kg/day DBP; this may have reached statistical significance if more litters had been studied.
The visual comparison of the cellular distribution of GFP-Atx3 15Q or 70Q with their respective K0 variants pointed to a slightly increased nuclear localization of the latter, whereas 70Q constructs carrying single lysine residues at positions K8 or K85 did not show a clear trend toward ataxin-3 compartmentalization ( Figure 2A ).
Differences between the mixed lipid and POPC were less apparent: a clear trend of increasing K M from liver lipid => mixed lipid => POPC is apparent by both assay methods (columns C, F, rows 7, 8, 9), but there was little difference in catalytic efficiency between the mixed lipid nanodiscs and the POPC nanodiscs (columns D, G, rows 7, 8).
Stratifications according to the administration of other baseline medications (in addition to a stable dose of levodopa) were not bound to provide a clear trend, since concomitant multiple adjunctive treatments at baseline were admitted in addition to levodopa; in fact, only few patients (10%) in the pooled studies ITT population had no additional baseline treatments, i.e., were receiving levodopa as their sole dopaminergic treatment on entering the studies; the majority of patients (90%) had indeed one or more concomitant baseline treatments, and thus patient subgroups by single adjunctive treatment partlyoverlapped.
According to 2022 data from the International Agency for Research on Cancer (IARC), approximately 20 million new cancer cases were diagnosed worldwide that year, with the cancer burden continuing to rise and a clear trend toward younger age of onset. 1 , 2 In the same year, the number of new cancer cases in China was estimated at 4.82 million, of which 39% (approximately 1.87 million cases) occurred in young and middle-aged individuals. 3 , 4 As the backbone of society and families, young and middle-aged patients wi
For Pi although a clear trend was not observed, two scenarios were noteworthy; when across environment heritability of GY was high (>0.55) for instance in EYT2011-12 and EYT2014-15 ( Table 1 ), no variation was observed among models 2, 3, and 4 and they performed equally well over the base model in EYTs ( Figure 4 and Supplementary Table S12 ).