“a clear trend”

In addition, we did not find a clear trend whether patients in different tumor stages were more or less likely to receive care in certified care networks.

The incidence of potential immunogenicity‐related adverse events did not indicate a clear trend in any positive ADA patient category compared with ADA ‐ NEG patients through weeks 52–64.

A clear trend to higher current densities with higher Cr content is observed.

There is a clear trend: as the concentration of ruthenium rises, the value of C dl grows steadily.

There is a clear trend to an increase in steps taken by those whose mBKS improved and a decrease in steps taken by those whose mBKS deteriorated.

In the current study, we observed that the values of all cephalometric measurements in the DS group showed a clear trend to be lower than the values of the normal counterparts (Figures 2 - 3 ).

Peaks below a fluorescence threshold level of 50 were excluded except where a clear trend of same t-RF was detected in other samples.

Conclusions The management of DFUs has significantly advanced over time, with a clear trend toward a compact, patient-centered, multidisciplinary approach.

A clear trend was observed of decreasing size of microspheres as the surfactant ratio of Tween 80 to Span 80 decreased.

Normalization to tumor size influenced the vWF results and blood vessel counts in both CMC and FMC, although a clear trend of increased blood vessel counts in grade III compared to grade I and II CMC as well as in grade III compared to grade I/II FMC remained detectable (Additional file 10: Figure S7A, B).

Figure 7 demonstrates a clear trend, with the higher grade reinforcement exhibiting larger yield drift ratios followed by relatively shorter ultimate strain in the beams and columns.

Testosterone complications As awareness continues to grow for testosterone deficiency in the media as well as the health care community, a clear trend demonstrating a rise in testosterone replacement treatment is seen.

In Figure 6a , there is a clear trend of contact area improvement with an increase in temperature from T = 20 °C to T = 80 °C as a function of η.

After an exhaustive revision of these methods, a clear trend in the use of nanomaterials for the determination of these cosmetic-related compounds has been observed, in line with the general trend observed within the analytical chemistry field.

When clusters 7 and 8, which also consist mainly of primary tumor cells and have low MMS scores, were used as root cells, the pseudotime analysis did not reveal a clear trend of increasing MMS scores along the pseudotime trajectory (Fig.

A truncating insertion to amino acid 266 was chosen as the representative ALE mutation to pykF for the toxic isobutyric acid condition since it represents a clear trend in disrupting the PykF subunit interfaces and manifested in two independent ALE replicates with this selection pressure ( Figure 1 workflow step 5.3).

Although the apparent multifunctionality of most of the accessory proteins of the ORPV ( 1 ) complicates analysis of the gene loss patterns among sets of genes involved in the inhibition of the same defense pathway, a clear trend is noticeable.

Length of hospitalisation across treatment groups was not statistically different, although there was a clear trend that patients treated with Clinda had the shortest length of stay.

Notable findings included: (1) while we observed a clear trend of increasing anti-LPS and anti-flic IgA and IgG concentrations over the first year of life, anti-flic and anti-LPS IgA were both lower than in our Boston controls; (2) anti-LPS IgA correlated significantly with serum CRP, AGP and Reg1 at 6 months and with fecal MPO at 9 months; (3) high anti-LPS IgA levels at 6 months of age and higher anti-flic IgA levels at 9 months of age were associated with a trend to greater decrease in LAZ scores over 18 months; (4) Compared to children in first quartile of anti-LPS IgA level, those in the second and third quartile had an increased risk of stunting.

As expected, the albumin affinity of 2a ( k ′ = ∼13.3) was higher than that of lixisenatide and 1f, for 2b–2d with OEG spacers, there is a clear trend that with increasing length of the OEG spacer, the compounds display an increased affinity to albumin binding relative to 2a (2b, k ′ = ∼14.1; 2c, k ′ = ∼15.2; 2d, k ′ = ∼17.2).

However the mouse data on the Cyp2a isoforms do not seem to explain the trend of increase in plasma metronidazole at 2 hours; in fact there was a clear trend of decrease in CYP2A enzyme activities to a greater extent in SPF mice than in GF mice (opposite to the expectations) at 2h.

For both, MFAP4 and fibroscan a clear trend towards higher values in stages F3 and F4 was evident ( Fig. 1 ).

Our age-specific analyses revealed a clear trend of increasing death rates of TBL cancer attributed to occupational exposure to PAHs in older age groups, particularly among individuals aged 55–74 years, with notable disparities across regions with different SDI levels.

1 , a clear trend of lower smoking cessation probability for higher levels of deprivation was evident; the least deprived neighbourhood decile had the highest crude incidence rate of quitting at 236.99 (95% CI 224.02, 250.71) per 1,000 person-years, while the most deprived decile had the lowest rate at 161.29 (95% CI 151.31, 171.93) per 1,000 person-years (Table 2 ).

As shown in Figure 4e , there is a clear trend toward greater hydrophilicity upon NP incorporation.