Among these metabolites there was a clear trend of increased urinary abundance with increasing sTYR concentration; a relationship confirmed by the significant (FDR-adjusted p < 0.05) positive correlations observed between sTYR and all urine metabolites derived from phenylalanine, tyrosine, HPPA and HPLA with the exception of phenylalanine and HPPA-sulfate.
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There was a clear trend of decreasing of the antioxidant activities of SBT compared with SL and SGT ( p < 0.05).
After the adjustment, a clear trend was observed ( p < 0.05) in which higher back extensor strength was associated with increased AMM (r = 1.12) and BMM (r = 0.89).
Differently, SV didn’t exhibit a clear trend with the increased altitude ( P >0.05, Figure 2C ).
As the drying process advances, there is a clear trend of T 21 and T 22 relaxation times shifting toward lower relaxation times, coupled with a significant decrease (P < 0.05) in the corresponding integral areas, reflecting the gradual depletion of immobilized water within the muscle fiber structure and free water in the extracellular spaces.
Although a clear trend can be seen on Figure 11 , the consistency check did not provide a statistically significant improvement when combined with the image selection S sel ( p > 0.05 for the comparison of O optim and O optim + cc for the Precision, Recall, and IoU).
In all other cases, NN-PBRTQC showed a clear trend toward reducing tANPed, with half of the cases exhibiting statistically significant differences ( p < 0.05), which demonstrated its potential for improving quality control sensitivity.
This association followed a clear trend; the likelihood of treatment failure was highest in camels with multiple affections and decreased as the number of affections decreased ( p = 0.05; OR: 9.0; 95% CI: 4.3–9.94; Table 7 ).
However, there was a clear trend towards significance between OS and MSI status in IHC (HR= 2.11 (1.00–4.45), p = 0.05).
Unadjusted mean IQ shows a clear trend towards increasing offspring IQ score as parental age increases (p-values<0.05, Table 2 ).
Contrasting results were found for hepatic adiponectin, with significantly lower concentration recorded in fish fed the HFD compared with the control group ( P < 0·05), and there was a clear trend for dietary choline to increase adiponectin compared with the HFD group, although no statistical differences were found ( P > 0·05) ( Fig. 3 ).
The variability in soil C and N did not exhibit a clear trend with altitude (p > 0.05 for both) ( Fig. 1a ,c), whereas soil P increased significantly across the altitudinal gradient (p < 0.05) ( Fig. 1e ).
A 2021 cohort study of 30 OSA patients found that 73.3% reported xerostomia, and 20% had objectively measured hyposalivation, with a clear trend of worse symptoms in moderate to severe OSA (salivary flow: 0.28 mL/min mild vs 0.14 mL/min severe; p < 0.05) ( 67 ).
Notably, significant upregulation of the keratinocyte terminal differentiation marker filaggrin (FLG; + 308%; P < 0.001) and a clear trend towards an increase (+ 132%; P = 0.05) in transcript levels of the epidermal differentiation complex protein loricrin (LOR) was observed in skin from SGC707-treated mice (Fig. 4 C).
For counterintuitive utilitarian decisions, ‘need for cognition’ scores showed a clear trend towards a positive correlation with perceived difficulty ( r = 0.449, p = 0.05) while psychoticism ( r = 0.029, p = 0.46) was not significantly correlated with difficulty ratings.
At earlier timepoints, we saw a clear trend toward cerebral atrophy particularly in cortical regions in association with dilation of ventricles that reached statistical significance at 18 months (+9.0%, P < 0.05).
Although a clear trend was observed of heavier babies at birth to 6 months in the intervention group compared to the control group, the difference was not significant ( p > 0·05).
Strikingly enough, while car accident-related injuries decreased as well as minor injuries, there was a clear trend of exponential increase in the percentage of patients presenting with gunshot wound (0.9% vs 1.9, p < 0.05) and stab injuries (0.7% vs 2.5%, p <0.05), between pre-COVID and COVID periods, respectively.
5 A, DSS-stimulated colitis rats showed a clear trend of upregulation of p-NF-κB p65, p-STAT3 and p-JAK2 proteins, all of which were downregulated in rats treated with three treatments ( P < 0.05, P < 0.01 or P < 0.001).
In subgroup analysis based on the TNM classification according to the International Union Against Cancer/American Joint Committee on Cancer TNM Classification for Gastric Carcinoma (seventh edition), 10 although there were no statistically significant differences in 5-year overall survival of TNM stage I and II between the 2 groups [91.7% and 48.7% in the transthoracic group, and 90.2% and 43.1% in the transabdominal group, respectively, P > 0.05, Figure 1 B and C, hazard ratio (HR) was 0.87 (0.11 to 13.40) and 1.11 (1.61 to 2.06), respectively, P > 0.05], there was a clear trend toward improved survival of TNM stage III patients with the transabdominal approach [25.7% versus 37.2%, P < 0.05, Figure 1 D, and HR was 0.66 (0 43 to 0.99, P < 0.05)].
The OPLS-DA score plot showed a clear trend towards separation between the two groups, and the currently established discriminant model with R2Y cum = 0.366 ( P < 0.05) and Q2 cum = 0.129 ( P < 0.05) allowed for a valid distinction between the two samples, indicating that there were indeed metabolic differences between the case and control groups.
5 , a clear trend ( P = 0.05) towards higher TTV DNA AUC 0–14 was observed in patients who died (median, log 10 25.8 copies × days × mL−1; range 0–51.5) compared with survivors (median, log 10 2.95 copies × days × mL−1; range 0–39.9). 4.
A clear trend of decreasing of mechanical threshold and thermal latency could be observed in the endometriosis rats when compared with the sham operation group (* P < 0.05; Figures 7D, E ).
Comparable results were found for the selection of TC potency for infants with mild and adolescents with severe AD, in which being a GP and pediatrician was associated with prescription of lower TC potency, and a clear trend was found for TOPICOP-P scores (−0.03, 95% CI: −0.06 to 0.00, p = 0.05, in infants with mild AD and −0.02, 95% CI: −0.05 to 0.01, p = 0.12, in adolescents with severe AD).
However, a clear trend toward longer survival with low-NEO status was noticed, especially in the PEMBRO subgroup (27.8 vs. 16.2 months, p = 0.05, Fig.