“a borderline significant trend”

A borderline significant trend was set at p < 0.1. 4.7.

This analysis showed a borderline significant trend in lower CRP levels for the regular users of CLO (Supplementary Table 5 ).

Among them, cortisol was significantly decreased and its metabolite hydroxycortisol also decreased after metformin administration, although this difference was a borderline significant trend ( Figure 2a and 2b ).

Although several studies showed no significant difference of EPS among CYP2D6 variation, some of them showed a borderline significant trend.

Adherence to a ‘high-sugar’ diet was associated with a borderline significant trend for an increased risk of CVD and CHD events.

Results During 16.8-year median follow-up, we found positive associations between TV viewing time and breast cancer incidence with a borderline significant trend among total women and a significant trend among postmenopausal women.

The p value was 0.09, which may indicate a borderline significant trend.

Results A 2-way mixed analysis of covariance showed a significant decrease in BMI, BFM, and blood glucose at 3 months in the internet-based intervention group; the effect size for the BMI and BFM parameters was moderate to large, and there was also a borderline significant trend for DBP and insulin.

In women, a significant risk of CD8 high tumors was only observed for the 3 rd and 4 th quartiles of weight, with a borderline significant trend, and none of the anthropometric factors were associated with risk of CD8 low tumors.

We observed a borderline significant trend association between high fatigue (elevated scores of SOFI) and the risk of CVD.

There was also a borderline significant trend regarding the relationship between testosterone and Lp(a) with positive FH of P-CAD ( Fig 2 ).

In the ACCORD trial, there was a borderline significant trend towards cardiovascular benefit among the pre-specified sub-group analysis of patients with TG ≥ 204 mg/dL and HDL cholesterol ≤34 mg/dL when compared with other patients [ 52 ].

We noted a borderline significant trend towards more medical than surgical admissions in the After group, which might partially explain the higher mortality in this group.

Furthermore, rs140148185 (beta = 0.39; P = 2.73 × 10 –3 ; intron region) in GABRA5 and rs150101078 (beta = 0.13; P = 2.61 × 10 –3 ; intron region) in GABRB3 exhibited a borderline significant trend with sleep duration (Table 2 ).

In contrast, increased flow did not affect the elastic laminae content in PCSK6 deficient mice, but comparison between WT and KO mice exposed to increased flow revealed a borderline significant trend ( Figure 4 C,D).

Among PBC patients, AUC of ElastPQ for detecting significant fibrosis (≥ F2, 0.81, 95% CI 0.66–0.95) did not show a statistical difference compared with those of APRI (0.59, 95% CI 0.37–0.82) or FIB-4 (0.71, 95% CI 0.53–0.89), which also showed a borderline significant trend, as shown in Table 4 .

In the present study, no significant relationship was found between the basic clinical and pathological parameters and the presence of central fibrosis/hyalinization area, except for a borderline significant trend toward less frequent occurrence in higher-grade tumors.

7 There was no significant difference in mortality between the groups, and only a borderline significant trend toward fewer heart failure hospitalizations for those who received CRT.

The two groups significantly differed respect to number of perseverative errors in the M-WCST-sf, with a borderline significant trend for the SWC-sv error interference effect (see Table 1 ).

With a borderline significant trend, the potential moderator Self-monitoring of behavior was associated with larger effect sizes and the moderators Discrepancy between current behavior and goal and Information about social and environmental consequences with smaller effect sizes ( P <0.10).

However, the serum lipid levels of HcDCA- fed μMPs showed a borderline significant trend in comparison with those of HcD-fed animals, it seems difficult to completely exclude the possibility that the effect of CA supplementation is totally independent of serum lipid profiles.

In contrast, stratification by PD-L1 status in the same arm (IMPower150 ABCP) showed a less pronounced difference in survival outcomes, with an HR of 0.77 and a logrank p-value of 0.0539, suggesting a borderline significant trend but not a strong enough distinction between the PD-L1 high and low groups.

As continuous variables, bMMP2 ( p =0.021), but not bMMP9 ( p =0.250) levels were correlated to DFS, whereas bMMP2 ( p =0.098) and bMMP9 ( p =0.068) levels presented a borderline significant trend for correlation to OS.

In multivariable analysis, absence of DCIS and low PR expression remained independently associated with lower odds of SLNB positivity, whereas low Ki-67 showed a borderline significant trend towards higher odds of nodal metastasis.

CAF Alone A borderline significant trend towards a higher mRC favoring CAF + L-PRF vs.