Excerpts

The changes in ExitLOS and HistLOS are highly significant (P < 0.0001) but in opposite directions.

Most importantly, the LC3-II/LC3-I ratio, which measures autophagy activity, showed a highly significant increase in the iridocorneal region of the aging mice ( 4 months: 1.106 ± 0.21, n = 5; 18 months: 2.178 ± 0.10, n = 4; P < 0.0001, t -test) ( Fig. 2 C).

Statistical evaluation using a two-tailed unpaired Student’s t-test confirmed this increase was highly significant ( P < .0001), highlighting overnight phage amplification facilitated by metabolically active log-phase E. coli hosts [ 40 , 64 , 72 ].

Actual renal clearance during subnormothermic machine perfusion, however, yielded a much closer and highly significant correlation ( r 2 = 0·82; P = 0·0001) with ulterior kidney function upon reperfusion.

Marbling Score and REA The mean marbling score evaluated in both laboratories for the striploins of different experimental groups showed greater values for the CAB striploins than for the CTNA counterpart ( Table 1 ), with highly significant differences ( p < 0.0001).

However, univariate analyses indicated that these differences were highly significant for PC1 (F 1, 40 = 77.74, P < 0.0001), but non-significant for PC2 and PC3 ( P > 0.340).

Nevertheless, the reduction of phagosomal PtdIns4P was highly significant ( p < 0.0001; Figure 6F ), implying that PI4K2A is at least partly responsible for the reformation of PtdIns4P in late phagosomes.

GWAS p -values and R 2 effects were extracted and QTL selection criteria was carried-out based on standard conditions of significance: “highly significant” refers to P < 0.0001 and “significant” refers to P < 0.001.

One-way ANOVA test for fertilization, cleavage and blastocyst formation rates between the two groups was highly significant ( P ≤ 0.0001).

Statistical analysis revealed that the reductions in biofilm biomass at concentrations ≥6.25 μg/mL were highly significant (**** p < 0.0001) compared with untreated controls. 2.6.

SIRIUS follow-up results presented at ACC showed that the highly significant differences (p < 0.0001) between the CYPHER stent and bare metal control stent for all clinical event endpoints were sustained at 3-years.

The quadratic model for GABA yield ( Y , mM) was highly significant (F=39.65, p<0.0001, R 2 =96.59 %), with significant terms for MSG (p=0.0338), sucrose (p=0.0284), their interaction (p=0.0319), and quadratic terms for both MSG (p<0.0001) and sucrose (p<0.0001) ( Table 4 and Table 5 ).

29.37 kg/m 2 ± 0.17) than their counterparts without the disease, with both differences being highly significant ( p < 0.0001).

This demonstrated that the lipolysis/plasma lipid relationships were still highly significant ( P <0.0001) after correction for sex; age; body mass index; waist circumference; waist-to-hip ratio; nicotine use; treatment of type 2 diabetes mellitus, hypertension, or hyperlipidemia; and fat cell size.

Both platform and nozzle temperatures were highly significant ( p < 0.0001), and multiple interaction terms (X 1 X 2 , X 1 X 3 ) were significant, demonstrating a non-linear coupling between thermal boundary conditions and dose accuracy.

There was a highly significant relationship between reduction in ESV and SDI (P<0.0001) as well as a greater than 15% improvement in EF and SDI (P<0.0001) (see figure 1 and table 1 ).

Low- and High-Temperature Effects The Fraass fragility point determination revealed highly significant ( p < 0.0001) effects of HS and WS, in both control and short-term aging, on low temperature performance.

Using the OPSCC TCGA cohort we demonstrated that HPV-associated tumors abundantly overexpress CDKN2A RNA with an average of 34-fold elevation ( Supplementary Table 6 in S1 Table s) that is highly significant (p < 0.0001, S7 Fig B ).

Likewise, BEAF + and CP/CH + boundaries on chrX show a highly significant difference in insulation between males and females (Wilcoxon test p -value < 10 −4 ) (Fig. 4e and Supplementary Fig. 8e ).

The Cochran Q's test for heterogeneity for all variables gave p-values which were highly significant (p < .0001).

The effects on tumor growth between the experimental groups were highly significant: shRNA ctrl versus shRNA UNG ( P < 0.0001), shRNA ctrl plus FdU treatment versus shRNA UNG ( P = 0.003), and shRNA ctrl plus FdU versus shRNA UNG plus FdU ( P = 0.003).

Friedman’s test proved that the effect of the stimulus on perceived fear was highly significant (chi-square = 6130.252, df = 41, P < 0.0001).

In contrast to that, upon additional expressing of Jv, a highly significant increase ( p < 0.0001) in ectopic actin bundle length (16.1 ± 3.4 μm) and width (0.47 ± 0.01 μm) was evident ( Figure 1 E, Table 2 ).

Comparison of gene expression levels obtained from RNA-seq and qRT-PCR showed a highly significant Pearson correlation coefficient (r) (M1: r = 0.9509, P < 0.0001; M2: r = 0.9242, P = 0.0004; Fig. 3d ).

The reliability between the 2 readers was highly significant ( P < 0.0001).