Striking features of this record includes a decreasing trend of −0.0015 ± 0.0002 pH year −1 from AD 1838–2001 (R 2 = 0.63, p < 0.0001) and inter-decadal variations with amplitudes of 0.1–0.2 units ( Fig. 2b ).
Excerpts
A Kruskal-Wallis test indicated that the difference in NPRA expression among the seven diagnostic groups was highly significant (p < 0.0001).
For aPTT the R 2 value was 0.36 highly significant ( P < .0001) but the median value resulted (36.2 seconds, 95% CI: 35-36.8 seconds) very close to the normal range (25-35 seconds).
All vaccinated groups showed 0% mortality when challenged, which was highly significant compared to the non-vaccinated controls (40 and 28% mortality eight and twenty-six weeks post vaccination (wpv), respectively) (P<0.0001).
Specifically, p < 0.05 indicates a highly significant difference, while p < 0.0001 denotes an extremely significant difference, and p > 0.01 suggests no significant difference.
We examined the socio-demographic elements that affect people’s awareness of the osteoporosis condition, and we found that there is a highly significant correlation between work environment and osteoporosis knowledge (p-value = 0.0001).
We found a highly significant positive correlation between nuclear ERβ and ovarian cancer marker CEA ( p < 0.0001; 95% confidence interval (CI) 0.1598–0.4465) (Table 4 ).
The liposome-based neutralization test results correlated excellently and were highly significant with those of the pVNT ( Table S6 ), for both overall comparison (Spearman R = 0.86, p < 0.0001) as well as variant-specific comparison (all R > 0.9, all p < 0.00024) ( Figure ).
Figure 3 shows the OR (95% CI) , where the history of GDM was found to be a highly significant risk factor with OR 3.91 (95% CI) (1.93 to 7.95) (p<0.0001).
Dance-compound introduction resulted in a highly significant increase in the number of dance bouts versus the solvent control (t = 5.16, d.f. = 39, Tukey-Kramer adjusted p<0.0001).
Analysis of cancer genome datasets (TCGA and GTEx) revealed greater NLRP3 and IL-1β expression in cutaneous melanoma samples ( n = 469) compared to normal skin ( n = 324), with a highly significant correlation between NLRP3 and IL-1β ( P < 0.0001).
According to data published by the Companion Animal Parasite Council website ( www.capcvet.org ), the percentage of Ohio dogs tested positive for exposure to the Lyme disease spirochete by the SNAP 4Dx Plus Test was 0.39% (218 of 54,963) for 2011, 0.55% (250 of 45,376) for 2012, 0.56% for 2013 (543 of 96,016), and 0.62% (102 of 16,343) for 2014 as of April 23, 2014, showing a significant trend of increase ( P < 0.0001, Chi-square test for trend).
Mettl5 and Mettl3 exhibited a similar expression pattern, peaking on Day 1 with highly significant upregulation ( p < 0.0001).
Averaged across the three settings, the mean Clarity ratings of the four sound scenarios were 62.0 (Scenario 9), 43.9 (Scenario 10), 52.9 (Scenario 11), and 35.1 (Scenario 12), and the ANOVA showed a highly significant main effect of Scenario ( p < .0001, see Table 3 ).
Nucleoplasmic bridges ( Figure 5b ) showed a weak bystander effect for GM15510 (p = 0.052), and for GM15036 the effect was highly significant (p<0.0001).
GTACG haplotype of SH2B1 has a highly significant association with responders (P< 0.0001).
Two-tailed test of independence indicated that the association between the mortality and PBO pre-exposure is highly significant (χ 2 = 84.51, df = 1, p < 0.0001).
There was a highly significant positive correlation between glucose and glycogen (Spearman r = -0.4102, p<0.0001, S1A Fig ), and a negative correlation between pH and glycogen (Spearman r = -0.5418, p<0.0001, S1B Fig ).
Two-way ANOVA revealed highly significant main effects of both cell type (F 1,14 = 89.42, p < 0.0001) and ZnO concentration (F 3,14 = 11.00, p < 0.001), with no significant interaction effect (F 3,14 = 1.25, p = 0.326), indicating that the differential sensitivity pattern remains consistent across all tested concentrations.
The results were statistically highly significant (P<0.0001).
While these effects were highly significant (overall p < 0.0001), the differences in intake were small and not clinically meaningful.
The ANOVA results ( Supplementary Table S1 ) demonstrated that the regression model was highly significant (F = 88.02, p < 0.0001).
In V1, the effect of eccentricity on BOLD response was highly significant ( F (1,23898) = 37.8; p < 0.0001; Cohen's f 2 = 0.319), indicating a strong relationship.
When considering only the change from the capital-adjusted model, surgical volume accounted for 54% of the remaining variation, and this improvement was highly significant ( p < 0.0001) ( Table 5 ). 4.
Mixed-effect analysis showed highly significant effect of epoch for mouse F53 [ F (5.339,353.3) = 4.973, p = 0.0001] and mouse F46 [ F (5.346,336.8) = 3.024, p = 0.0093] ( Figure 7B ).