Barely Significant

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highly significantP < .00010.0× alphaqualifiedgold
A combined analysis indicated a significantly greater reduction in the VPB burden associated with acupuncture treatment when compared to pharmacological therapy (relative risk, 1.16; 95% CI, 1.08–1.25), with no significant heterogeneity (I 2 = 0%) and a highly significant P value ( P < .0001), as illustrated in Figure 2 .
highly significantP < 0.00010.0× alphaqualifiedgold
Statistical analysis and modeling Factorial model validation The statistical analysis of the quadratic models for responses (PS, PDI, and ZP) across the three preparation methods revealed that the selected factors (CPPs) significantly influenced the responses (CQAs), as indicated by the highly significant model p-values ( P < 0.0001).
highly significantP < 10 −40.0× alphaqualifiedgold
Using a degree‐constrained method of permutation to test the null ( H 0 ) versus alternative hypothesis ( H 1 ) of whether the number and degree distribution of disease‐causing genes account for the number of disease subnetworks, in each case the observed number of disease subnetworks is highly significant ( P < 10 −4 ; Supp.
highly significantp < 0.00010.0× alphaqualifiedgold
For sub-lineage K-IIc, both neutrality tests were strongly negative and highly significant (Tajima’s D = −0.0850, p < 0.0001; Fu’s Fs = −27.7220, p < 0.0001), jointly pointing to a pronounced excess of rare haplotypes consistent with a recent and rapid population expansion.
highly significantP <0.00010.0× alphaqualifiedgold
Under mild Tetracycline treatment (0.01% over five generations) however, the AM semispecies produces a highly significant sex bias towards males (ratio males to females = 1.79, χ 2 = 43.27; d.f. = 1; P <0.0001), whereas the OR semispecies did not deviate from the usual 1∶1 sex ratio ( Table 1 ).
highly significantp < 0.00010.0× alphaqualifiedgold
A highly significant reduction ( p < 0.0001) was also found in the invasion of the co-culture by the HMLN-1 strain when it was co-inoculated (65.6%) and pre-inoculated (97%) with L. reuteri M4-100 ( Figure 3 ).