23 % (109/467) of our DEGs were shared, this overlap being highly significant (hypergeometric test p -value < 0.0001).
Excerpts
Across all responses, the positive coefficient of the curing period (Factor B) was found to be highly significant ( p < 0.0001), indicating that longer hydration time is the strongest contributor to strength development, primarily due to progressive hydration and pozzolanic conversion of SCMs into additional C–S–H gel.
The interaction between these three factors (group, side, and CN) was also highly significant ( P < 0.0001) ( Table 1 ).
Highly significant heterogeneity was found among these 2 studies ( χ 2 = 19.43, I 2 = 95%, and P < 0.0001), indicating their heterogeneity. 3.3.2.
Post hoc Tukey's multiple comparison analysis between groups [ Table 3b ] indicated that mean of most of the treatment groups was highly significant ( P < 0.0001).
In the 325 mg cohort, plasma salicylate (1061–6299 ng/mL) and salicylurate (673–3355 ng/mL) were detected in 21/21 (100%) subjects ( Figure 4 B), gentisic acid (39–283 ng/mL) was detected in 20/21 (95%) subjects, and salicyl acyl glucuronide (31–396 ng/mL) was detected in 21/21 (100%) subjects ( Figure 4 C) following ASA exposure and were highly significant ( p < 0.0001 for each metabolite, paired t -tests).
The analysis of all SIV-infected animals revealed a highly significant inverse correlation between the viral RNA load in plasma and the CD4+ T-cells in blood ( P < 0.0001; r = -0.786), BAL ( P < 0.0001; r = -0.814), duodenum ( P = 0.008; r = -0.497) and colon ( P < 0.0001; r = -0.685) as well as for the proportion of CD4+CCR5+ T-cells in blood ( P = 0.0003; r = - 0.647), BAL ( P < 0.0001; r = - 0.817), duodenum ( P < 0.0001; r = - 0.742) and colon ( P = 0.0003; r = - 0.674).
This interaction term improved model fit and was highly significant in explaining skilled birth attendance (p<0.0001), with older women experiencing a greater increase in odds of SBA per child delivered as compared to younger women, and is in line with previous findings.[ 16 ] While similar patterns were observed among ANC and PNC outcomes, these effects were not significant.
The difference in stop codon usage between 500 HEGs and 500 LEGs is highly significant based on chi-squared test with Yates correction for continuity (χ 2 = 91.23, DF = 2, P < 0.0001).
The model was highly significant (Chi-Square = 264.87 (12), p < 0001) and accurately placed 81.6% of the sample into their respective group (Actives versus Withdrawals).
When the eight single‐genotype variants were combined and compared against the WT parental virus treatment, there was a highly significant difference between the two types of virus treatments, that is multiple‐genotype WT vs. single‐genotype variants (treatment: χ 1 2 = 24·81, P < 0·0001), with the slope of the relationship between virus dose and virus‐induced mortality being steeper for the WT virus (log 10 dose × variant: χ 1 2 = 4·66, P = 0·025).
A highly significant inverse correlation could be observed between SNAI2/SLUG and ESR1 mRNA expression (p < 0.0001).
The difference between HR on admission, 12 h and 24 hours was highly significant (p < 0.0001).
As expected, both the total differentiation and differentiation along each of the two first axes, were highly significant (global F ST = 0.19, p <0.0001; PCA1 F ST = 0.050, p <0.0001; PCA2 F ST = 0.046, p <0.0001).
The difference in the success rate of PALs within singletons and clusters, defined as the proportion generating polymorphic banding patterns consistent with a single locus, was highly significant (29/48 versus 5/48; two‐tailed binomial proportions test, χ 2 = 24.1, df = 1, P < 0.0001).
The differences between the mean STAT, MAT, and IHA titers of infected cattle and healthy vaccinated cattle were highly significant (p<0.0001, p<0.005, and p=0.0002, respectively).
The liposome-based neutralization test results correlated excellently and were highly significant with those of the pVNT ( Table S6 ), for both overall comparison (Spearman R = 0.86, p < 0.0001) as well as variant-specific comparison (all R > 0.9, all p < 0.00024) ( Figure ).
Result Foot reflexology showed a significant difference (P < 0.05) in systolic and diastolic blood pressure and a highly significant difference (P < 0.0001) in anxiety and pain.
In the subgroup with low or intermediate risk of recurrence the differences in the recurrence-free survival did not reach statistical significance (p = 0.36), however, in high-risk cases there were highly significant differences among the surgical groups (p <0.0001, Figure 2 ).
Compared to the control group, the study group males showed a mean decrease in weight of 1.44 kg, and this difference was highly significant ( P < 0.0001) [Tables 3 – 5 ].
Using a degree‐constrained method of permutation to test the null ( H 0 ) versus alternative hypothesis ( H 1 ) of whether the number and degree distribution of disease‐causing genes account for the number of disease subnetworks, in each case the observed number of disease subnetworks is highly significant ( P < 10 −4 ; Supp.
The two primary questions that we addressed in this study were (1) are there differences in the relative expression among the five AQPs within the amnion and (2) do AQP mRNA and protein levels correlate with IMA rate when IMA rate is experimentally altered? With respect to the first question, the recalculation indicated that in the control group, the highly significant difference in AQP mRNA levels ( P < 0.0001) remained with the added result that the difference in mRNA levels between AQP3 and AQP9 reached statistical significance.
In this example, the reductions in response size relative to rest were statistically highly significant in all three phases of rearing (one-way ANOVA, p < 0.0001, F (3,135) = 21.77; Dunnett's multiple comparison test comparing each phase; p < 0.01 for all comparisons).
In addition, the quadratic term X 3 2 (LOR2) was highly significant ( p < 0.0001), along with a large negative coefficient (−272.987), confirming the strong nonlinear suppressive effect of higher LOR concentrations on the nanoparticle size.
Despite this observed variability between immune responses at 7 days p.i., the difference in proliferative responses to viral and myelin antigens in infected and control groups was highly significant ( p <0.0001).