A highly significant correlation [r = .95 (p <.0001)] was observed for channel 4 ( Fig 6 ).
Excerpts
Using GREAT, we found that about 77% of the genes associated with active TFAP2A peaks are also associated with active MITF peaks, a highly significant overlap (hypergeometric test, p<0.0001) ( Fig 3D ).
Calendar year explained 79% of the observed variance (R2 = 0.786), indicating a substantial acceleration in treatment initiation over time, the slope of this decline was highly significant ( P < 0.0001).
ParaHIT Total showed lowest sensitivity (OR 0.08, 95% CI 0.04 - 0.19) and highly significant statistically (P < 0.0001).
Each of the five subspecies showed highly significant population genetic differentiation ( p < 0.0001) by pairwise F st and R st with 10,000 permutations ( Table 5 ).
A highly significant association was seen between early PSA recurrence and elevated ADAM15 expression ( Figure 4 A , P < .0001) in all tumors and also in subgroups of ERG fusion negative and positive cancers ( P < .0001, P = .0002); ( Figure 4 B and C).
All regressions were highly significant ( F -value = 352.31, and p -value < 0.0001 for CLD % and F -value = 276.91, and p -value < 0.0036 for TS), and also the R 2 coefficients were adequate (0.988 for CLD %, and 0.998 for TS), demonstrating the models are suitable for representing the responses.
The difference between the distribution center of the two subpopulations was highly significant [ F (6, 85) = 11.246, P < 0.0001].
The results indicate that comparisons evidenced highly significant correlations between values computed by the lumped model and simulated mechanical model for both networks with p < 0.0001.
Niche expansion was found to be higher in species with high dispersal distance, with high mean SLA and seed mass (only marginally significant), and high seed mass variability, in annual species, and those introduced from temperate and tropical biomes ( φ = 5.5; p < 0.0001, R 2 = 0.51, d.f. = 10; Figure 2a,c for specific examples).
Analyzing all ten eggs together, repeated measures ANOVAs were highly significant across the eight time periods for all three direct spectral variables: incident light caused a decrease on average reflectance (F 8, 72 = 11.81, p<0.0001), a decrease in the height of the blue-green peak (of the seven blue-green eggs) relative to the surrounding areas of the spectrum (F 8, 48 = 11.50, p<0.0001), and the height of the UVB peak (F 8, 72 = 11.39, p<0.0001) ( Fig. 4 ).
Furthermore, contingency analysis showed that there was a highly significant increase in TPβ expression between benign/BPH versus Gleason 3/4/5, Gleason 3 alone, and also Gleason 4/5 ( P < 0.0001, all; Table 1B ).
Mean difference between postsurgery clinical versus postsurgery CBCT measurements was 0.93 mm which was statistically highly significant ( P < 0.0001), indicating underestimation of postsurgery clinical measurements compared to postsurgery CBCT measurements [ Table 2 ].
Of these SNP, rs29025980 showed a highly significant ( P < 0.0001) departure from Hardy Weinberg Equilibrium (HWE) in almost all groups tested (5 out of 8 breed types).
Our analyses identified the following variables as highly significant: “mean age,” “number of age groups”, and “data reporting quality” (all p < 0.0001). “Setting,” “disease classification,” and “number of diseases in the classification” were significant (0.01 < p ≤ 0.03), and “data collection period” and “data source” were non-significant.
DFA on CON versus ADD groups utilizing all factors was highly significant ( p ≤0.0001).
This linear trend of increasing total STarT-G score with an increasing number of somatic symptoms was highly significant (Jonckheere–Terpstra test, P < 0.0001).
PERMANOVA confirmed a highly significant effect of time (weeks) on microbial community structure (F = 60.664; P = 0.0001), whereas treatment had no significant standalone effect (F = 0.8889; P = 0.4175; Fig. 6 ).
Although the linear effect of saponin concentration was not statistically significant (F = 3.39, p = 0.0814), the quadratic effect was highly significant (F = 117.50, p < 0.0001), confirming the curvature of the response.
There is a highly significant correlation between the two measures ( R = 0.66; P < 0.0001) (Additional file 1 : Figure S4); whilst this is not a strong relationship, it is consistent with previous observations between these two measures ( R = 0.61) [ 6 ].
5B,C , tumor growth was significantly inhibited by Trametinib exposure (p = 0.0009), while Everolimus-treated tumors did not significantly differ from vehicle control-exposed tumors in either their final size or their growth rate; however, combined treatment with Trametinib and Everolimus resulted in highly significant growth inhibition, as compared to either vehicle control (p = 0.0001) or single agent treatment (p = 0.003 for the comparison between Trametinib and combination; p = 0.0026 for the comparison between Everolimus and combination).
Repeated-measures ANOVA revealed a highly significant effect of time ( F 37,962 = 34.6; p < 0.0001) on body mass variations (Fig. 1 a).
ANOVA revealed large and highly significant effect of association strength on error rate ( F (1,32) = 167.6, p < 0.0001; η 2 =0.84) and reaction times ( F (1,32) = 325; p < 0.0001; η 2 = 0.91).
Effects of v init on a max were statistically highly significant ( F 3, 213 = 1287, P < .0001).
Strikingly, there was a highly significant correlation between the level of hypomethylation of all 12 CpG sites and the level of mRNA expression ( P < 0.0001) (Figure 5C and Supplementary Figure S1 ).