Excerpts

The changes with time were, as expected from earlier studies (Lee et al.,, 1991a) very highly significant, but more interestingly so was the interaction between time and dose (P<0.0001).

As presented in Table 7 , the ANOVA results indicate that the factors of models A, B, C, D, AC, BC, BD, CD, A 2 , B 2 , and C 2 are D 2 < 0.05 (at the 95% confidence level, p < 0.05 was considered statistically significant and p < 0.0001 was considered statistically highly significant) [ 14 , 20 , 21 ], indicating that the effects of the nitric acid concentration, leaching temperature, liquid–solid ratio, total pressure, as well as the interactions between these factors and their squared effects on the vanadium leaching efficiency were significant.

Compared with less intensive regimens, more intensive regimens produced a highly significant 15% (95% CI 11–18; p<0·0001) further reduction in major vascular events, consisting of separately significant reductions in coronary death or non-fatal myocardial infarction of 13% (95% CI 7–19; p<0·0001), in coronary revascularisation of 19% (95% CI 15–24; p<0·0001), and in ischaemic stroke of 16% (95% CI 5–26; p=0·005).

faecium ( n = 37) were gelatinase-positive and their correlation was highly significant (chi-square p = 0.0001, Fisher’s Exact test p = 0.0001) ( Table 6 ).

A mixed model for repeated measures was used to determine predictors of LVMi change over time and was found to be highly significant overall in predicting LVMi change (p<0.0001).

Statistical analysis showed a near-perfect agreement between the two methods, with a Cohen’s Kappa coefficient of 0.93 and a highly significant association by Fisher’s exact test (p < 0.0001).

Differences in serum anti-N IgG titers between hamsters immunized with the MN vaccine, alone or in combination with S protein vaccines, and sham- or vector-immunized hamsters were highly significant at both Week 3 and Week 8 ( P < 0.0001) (Fig. 7d ).

Critically, the main effect of Emotion type was highly significant [ F 1 (1,59) = 200.95, p < 0.0001, η 2 = 0.23; F 2 (1,18) = 8.84, p < 0.009, η 2 = 0.27], as putatively basic emotions ( M = 5.72) were rated higher than non-basic emotions ( M = 4.61).

The P -values resulting from the comparison made by the exact unilateral binomial test (the number of homozygous profiles observed does not exceed the expected number calculated with the observed number of blanks) between the number of observed and expected homozygous profiles was highly significant ( P -value < 10 −4 ).

The analysis also quantified the influence of parameters on TPPs yield through standardized coefficients: liquid-to-solid ratio (X 3 ) and ultrasonic temperature (X 4 ) were highly significant ( p < 0.0001), followed by ultrasonic time (X 1 ) ( p = 0.005) and ultrasonic power (X 2 ) ( p = 0.0049).

When the combined group of 8 patients with hypercalcaemia is compared with the control group the difference is statistically highly significant (Mann Whitney, U Test P=0.0001).

As for night-time, wakefulness during daytime, occupied the highest proportion (60.4 ± 1.8%) compared with the percentages of drowsiness, NREM sleep and REM sleep (9.4 ± 0.8%; 23.4 ± 1.5% and 6.7 ± 0.6%, respectively) and these differences were found to be highly significant (p < 0.0001; p < 0.0001; p < 0.0001) ( Fig 5C ).

As expected, FSHD2 patients showed a highly significant (Mann–Whitney U test; p < 0.0001) D4Z4 hypomethylation (11 ± 7%; range 3–30%) compared to controls (51 ± 12%; range 19–76%).

t-tests between driver heterozygote control flies and flies expressing UAS -rl sem showed highly significant effects on pupal size (t (55) = 18.68, p<0.0001, n>25).

In addition, the RGR showed a decreasing trend with increasing seed mass, regardless of population and year of collection (Seed Mass: F 1,643 = 174.16, P < 0.0001).

Comparing pre- and postsplenectomy HCT values to the threshold HCT value required for isovolemic hemodilution (HCT = 23%) revealed that splenectomy resulted in a highly significant increase ( p < 0.0001) above the threshold.

Intraclass correlation coefficient (ICC) The ICC values were highly significant (p < 0.0001) for all the measurements, thus rejecting the null hypothesis (Table 3 ).

A highly significant effect for the dose variable was found (F(5, 38) = 122.5, p < 0.0001), indicating that different doses resulted in significantly different blood glucose concentrations.

The cross-sectional analysis of the LTSS showed a trend toward lower prevalence of S. aureus in the ivacaftor-treated versus the modulator untreated comparator cohort in 2014 (63.9% vs. 69.9%; p < 0.0001 in the US cohort and 29.8% vs. 33.9%; p = 0.1706 in the UK cohort) and of MRSA (23.3% vs. 29.4%; p < 0.0001 in the US cohort and 2.7% vs. 3.7%; p = 0.42 in the UK cohort) [ 29 ].

The cumulative analysis of all sites demonstrates that vaccination resulted in a highly significant reduction of the frequency of positive rated animals in the vaccinated group (59 out of 439, 13.4%) compared to the unvaccinated group (88 out of 270, 32.6%; p < 0.0001).

Moreover, the correlations between the concentrations of free and total (free plus conjugated) species of methyl and n- propyl parabens were highly significant ( p < 0.0001 and p = 0.0096, respectively; Figure 2 ).

For VAY, all linear effects (X 1 2 , X 2 2 , X 3 2 ) and interaction terms were highly significant ( p < 0.0001), with the linear term of extraction time (X 1 ) in UAE and the liquid–solid ratio (X 2 ) in WBE displaying particularly significant. 2.2.2.

There was a highly significant association between the spa and agr type ( p < 0.0001), and for most spa -CCs, all isolates belonged to a single agr type.

Analysis of Variance (ANOVA) The ANOVA results in Table demonstrate that the developed quadratic Model is highly significant ( P -value <0.0001, F -value = 344.57), confirming its excellent predictive capability, and the Lack-of-Fit test is nonsignificant ( P -value = 0.0534), validating the model’s adequacy.

In figure 2 , changes in the total score of adherence to treatment were compared between the control and intervention groups, which indicated an increasing trend in the mean total score of the intervention group within the first, third, and sixth months, compared to the pre-intervention stage (P=0.0001).