Excerpts

Specifically, for ROC-AUC, the differences were highly significant versus ChemBERTa ( t = 11.99, p < 1 × 10 −11 ) and CLAMP ( t = 10.23, p < 1 × 10 −10 ).

Highly significant differences were observed in the level of clustering, or transitivity ( F = 86, p = 10 −11 ), however, with the antigens showing strong clusters separated from each other.

2014 ), and found highly significant overlap between networks constructed using ENCODE data from mouse adult and fetal brains (hypergeometric overlap test P -values <10 −11 ) compared with a random brain TRN with the same TFs and targets (for further details, see Supplemental Methods ).

Expanding the observation to cells that showed morphological changes, including elongation, that preceded divisions, another 87 cells appeared to be preparing for division in aggregates while none of the isolated cells showed any shape change, which was a highly significant difference (24.3% vs 0%, two-sided p< 10 - 11).

In Mp toc1 ko mutants, expression of Mp PRR was continuously high and arrhythmic, as indicated by highly significant effects of both genotype (G) and genotype x time interaction (GxT) terms in ANOVA ( P < 10 −11 ), suggesting that MpTOC1 represses Mp PRR .

The preponderance of significant negative correlations with ORF length among eukaryotes is itself highly significant, for both 5′-mRNA folding energy (binomial P < 10 −11 ) and 5′-CAI (binomial P < 10 −9 )—suggesting a systematic eukaryotic trend toward faster translation initiation and faster early elongation in short versus long genes.

The overlap of these 952 AI genes with the 223 core breast ER- signature (Figure 1 ) was 51; by chance, around 19 genes would have been expected to overlap, which makes the observed overlap of 51 highly significant ( p = 1E-11, one-sided Fisher's exact).

A generalized linear regression model with output SRT benefit modeled just from avREOIG (i.e., SRT benefit ∼ 1+ avREOIG) showed both intercept ( p < 10 −22 ) and avREOIG ( p < 10 −11 ) to be highly significant factors with an overall r 2 = 0.371 ( p < 10 −11 ), that is, 37.1% explained variance.

The usual care plus albendazole arm continued, however, to show a highly significant difference in weight gain (2.8 [SE 0.1] kg vs. 3.8 [SE 0.1] kg, difference 1.0 [SE 0.15] kg, p = 10 −11 ), with the dewormed children exhibiting a 35 (SE 5) % higher weight gain.

In contrast, the difference between double conditions was large and highly significant (D + : median 1.27, D − : median: 0.63, z = 7.1481, Bonferroni corrected p < 10 −11 , Wilcoxon signed-rank test).

8 b) and had highly significant enrichment of interactions between them (STRING: expected number of edges: 5; number of edges: 28; PPI enrichment p-value: ****p < 1 × 10 –11 ) , while random samples of 43 peaks from either all GWAS ALS genes or from all epiChromALS peaks showed no functional enrichment, suggesting a mechanistic link between these genes, neuronal development/function, and epigenetic mechanisms.

The regression for the dress explained 9.2% of the variance and was highly significant (F(2497) = 25.0, p = 10 −11 ).

Permutation testing reveals that skewing in the 19p region is highly significant (p<10 −11 ).

Moreover, enrichment of ChIP-Seq peak counts at both motifs was highly significant (Wilcoxon rank-sum: p<1×10 −11 ).

2, A and B ), which is not considered a statistically significant increase (P = 0.8) but is highly significant when compared with spontaneous breaks in WT and 53BP1 KO cells (P = 1.01 × 10 −11 for WT and P = 0.00016 for 53BP1 KO).

Independent-samples t-test revealed that MD patients ( n = 31) displayed significantly higher Delta_TP_C-B values (Mean = 0.383, SD = 0.104) compared to SV patients ( n = 19; Mean = 0.162, SD = 0.040), yielding a highly significant difference ( t = 8.89, p = 1.04 × 10 −11 ).

Differences were highly significant ( p < 1.05e-11, OR = 7.67; Fig. 2 C).

The positive association between San ancestry and TB susceptibility was highly significant, whereas association with Bantu ancestry was relatively weak (p-value =1.06×10 -11 and p-value =3.00×10 -2 respectively) [ 8 ].

Overall between-group differences were highly significant ( p = 1.113 × 10 −11 ; p _adjust = 2.226 × 10 −11 ) ( Figure 2 A).

Formal meta-analysis of the replication cohorts was highly significant (OR = 5.2, 95% CI = 3.2-8.5, P = 1.2 × 10 −11 ).

1 E), including a highly significant increase in the abundance of Staphylococcus genus after transplant (Fig. 1 E, ANCOM-BC, p = 1.2 −11 ).

Meta-analysis using the inverse-variance method within METAL[ 29 ] resulted in a highly significant associations with neuroblastoma ( Table 1 ; rs6441201: P = 1.21x10 -11 , Odds Ratio 1.23, 95% CI:1.16–1.31 and rs3796727: P = 126x10 -12 , Odds Ratio 1.30, 95% CI:1.21–1.40; rs3796725: P = 2.08 x 10 −11 , Odds Ratio 1.29, 95% CI:1.19–1.38). rs3796727 genotype correlates with methylation status of C

However, when only the time of the recovery activity was considered, we observed highly significant differences in the caloric consumption between groups ( p = 1.22 × 10 −11 ; Figure 3A ).

4 b, the Kaplan-Meier analyses exhibited highly significant differences in time to overall survival between two different risk groups (hazard ratio [HR], 16.4; 95% confidence interval [CI], 5.68–47.3; p = 1.263e-11).

In general, the Kruskal–Wallis test indicated a highly significant association between subcutaneous fat thickness and the occurrence of fractures, regardless the experimental group ( p = 1.29 × 10 –11 ). 3.3.