Barely Significant

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a significant trendP < 0.0010.0× alphagold
Further, the number of sickle-shaped blood vessels was associated with distant metastasis and OS, with a significant trend toward a poor prognosis (metastasis P < 0.001, Cox; OS P < 0.001, Cox) observed for patients with more than 100 such vessels in large maximal tumor sections.
highly significantp < 0.0010.0× alphaqualifiedgold
Furthermore, Pearson correlation analysis between DMR methylation of these genes was also detected to be highly significant among these groups ‘r’ being 0.99 (p < 0.001), 0.83 (p < 0.05) and 0.82 (p < 0.05) for SNRPN vs PEG10 , SNRPN vs MEST and PEG10 vs MEST respectively.
highly significantp < 0.0010.0× alphaqualifiedgold
The other participants all showed a highly significant VWFA cluster on a single-subject level (FWE-corrected p < 0.001) and positive beta values when extracting the mean beta value for the “words versus checkerboards” contrast from a VWFA mask based on literature (see Methods section and Supplemental Material Sect. 1 for a description of the literature-based mask).