Excerpts

picta as indicated by the highly significant logistic regression of male proportion against wCTUs (Z = −15.15, P < 1 × 10 −15 ) (Fig. 3c ).

Analyzing the AMΦ data with linear models to control for batch effects, we found a highly significant effect of CSE concentration (p < 10 −15 ) on phagocytosis.

2 ), the global model was also highly significant (P < 10 −15 ) and explained 64.4% of the total deviance.

Analysis of the number of crystal packets among the studied species revealed highly significant differences in their frequency of occurrence (ANOVA, p < 10 − 15 ).

Quantification of glial nuclear basket ::GFP levels normalized to the oil vehicle control (1.0 ± 0.029, n = 13; 10 nuclei averaged per data point) shows a highly significant ~ 200% mean nuclear elevation following critical period EB experience (1.904 ± 0.030, n = 17; t (28) = 21.24, p < 1.0 × 10 −15 , two-tailed unpaired t- test; Fig. 5 B).

These “High DMRs” were found closer to the TSS of genes and had higher CpG density; there was a strong trend for increasing overlaps with CpG islands and shores with increasing ΔMe (χ 2 292.3 and 233.6 respectively, p < 22.e-16) with 4.5% and 27.8% of ≥0.3 DMRs overlapping CpG Islands or Shores respectively (Supplementary Fig.

In the case of PQ11 and PQ28, the very strongly positively correlated traits, the clusters of GBS, F87, and F24 showed extremely significant differences (p-value < 2.2e−15).

However, our reanalysis revealed a highly significant difference (p = 3.3e −15 ) using the same statistical test as in 1 due to the numerous, large LPF on mysticete palates (Fig. 3 b–f, Fig.

The overall regression was found to be highly significant (R 2 = 0.641, F(7680) = 173.2, p < 6.4 × 10 −15 ).

We found that the sep-1(ts) mutant grown at permissive temperature showed a highly significant reduction in the number of apoptotic corpses (average of 2.4 ± 1.2 corpses; n = 53; p = 6.4 × 10 −15 ) at the “comma” stage of embryogenesis compared to that in wild type (N2) embryos (average of 4.4 ± 1.2; n = 121; Fig. 1B ).

Of these, 31 genes appeared in both lists, with the change occurring in the same direction, a highly significant convergence (Fisher Exact test p = 1.9 × 10 − 14 ; Fig. 1 a).

Considering individual tree data, the difference in seed production between mast and non-mast categories of years was highly significant (ANOVA, F = 5.5485, P-value = 5.331 × 10 −14 ).

To evaluate the statistical significance of these differences, we performed a Friedman test, which revealed a highly significant effect of color on subjective glare perception (χ 2 = 64.60, df = 3, p = 6.1 × 10−14), confirming that glare responses varied significantly across the four colored scenarios.

Our multivariate linear regression model was overall highly significant (p = 1.10E-13; F = 15.71 on 9 and 70 degrees of freedom; adjusted r 2 = 0.63) and the residuals of the regression for the adhesive force were found to be normally distributed (p = 0.88; W = 0.99).

The ANOVA for GRI (day −1 ) indicated a highly significant effect for treatments (F = 16.89, p = 1.28e−13), however genotypes and genotypes × treatments interaction showed non-significant effects.

Tukey’s multiple comparison tests normalized to oil vehicle control innervation volume (1.0 ± 0.040, n = 13) reveals the expected highly significant innervation volume pruning with the stronger 25% EB critical period experience (0.150 ± 0.044, n = 10; q (39) = 20.56, p = 1.3 × 10 −13 ; Fig. 4 B, left).

There was also a highly significant enrichment of genes involved in response to bacteria and lipopolysaccharide (e.g. the category “Response to lipopolysaccharide”, P = 1.69 × 10 −13 ).

In the most comprehensive globally representative sample of Thoroughbreds to-date ( n = 10,118), including prominent stallions ( n = 305) from the major bloodstock regions of the world, we show using pan-genomic SNP genotypes that there has been a highly significant decline in global genetic diversity during the last five decades ( F IS R 2 = 0.942, P = 2.19 × 10 −13 ; F ROH R 2 = 0.88, P = 1.81 × 10 −10 ) that has likely been influenced by the use of popular sire lines.

We identified a highly significant enrichment of imprinted genes involved in the placental somatic duplications (21/1,180 duplicated genes vs 214/57,952 Ensembl genes; P = 2.67 × 10 −13 ) ( Table 4 ).

There was a significant trend of positive correlation between the risk score and the angiogenesis activity score (R = 0.32, p = 9.5e−13) (Fig. 7 J).

The genotypes (RIL and accession) had a highly significant effect in both populations ( P -values ≤ 9.92e−13).

An unanticipated outcome was the finding of a highly significant (p < 1 × 10 −12 ) relationship with up- and down-regulated genes encoding effectors of the DNA damage response, including BRCA1 , CHK2 and RAD51 , among many others (Supplemental Fig.

9B ) shows functions related to “Cellular Movement, Hematological System Development and Function, Immune cell trafficking and cell-mediated immune response”, with a highly significant score of 12 (p = 10 −12 ) (Fig. 9 ).

For heat resistance (CTmax), males became less tolerant with increasing age as we observed a significant negative slope with age in the regression (p = 7.91e-23), whereas for females, their resistance to heat is not changed with age suggested by the highly significant positive interaction effect (p = 1.20e-12) (Table 1 , Fig. 1B ).

As we observed in YPA, mRNAs encoding components of the mitochondrial electron transport chain (ETC) were highly significant targets of JHD2 -repression in YAR ( p < 2.6e-12, Supplementary Table 5 ).