Furthermore, the increase of percentage of centralized nuclei remained highly significant at the ages of 3 months (F (1, 24) = 60.27, p < 0.0001), 5 months (F (1, 28) = 66.91, p < 0.0001) and 10 months (F (1, 24) = 74.14, p < 0.0001), until the age of 15 months (F (1, 24) = 63.22, p < 0.0001).
Excerpts
Thus, we selected only the triplets with highly significant (28 out of 125, p-value < 1.00E-04) non-zero values, summarising them in Supplementary Table S6 B.
communis had a highly significant effect on a wide range of bacterial groups independent of the watering regime as obtained with an analysis of differential abundance (ALDEx2) ( P < 0.0001) (Supplementary Figure S2 , S3 , Table S2 ).
Relationship between the OD 490 values of anti-PvMSP9 antibodies A pairwise comparison of the OD 490 values for total IgG antibodies to antigens TMS102 and CT1186 displayed a highly significant correlation among sera from 246 patients (Spearman’s r = 0.825, p < 0.0001).
The model showed a highly significant value (p < 0.0001) (Table 3 ).
This analysis showed a highly significant positive correlation between the two datasets for both the SLC transporters (r = 0.9157, P < 0.0001) and the ABC transporters (r = 0.8368, P < 0.0001) (Fig. 3 , Supplementary Tables S3 and S4 ), providing further confidence in our approach.
Two-way ANOVA statistical summary demonstrated that the clinical status had a highly significant impact on these levels (F (1, 36) = 26.59, p < 0.0001).
In the second stage, SNPs/loci that passed a significant threshold (p < 0.05) were further pruned down with bonferroni correction and only those SNPs that were highly significant (p < 0.00013, Supplementary Table 3 ), and belonged in particular, to the extracellular matrix (ECM) i.e., Aggrecan and Fibulin-1 genes were selected for genotyping, as these genes were up-regulated and associated with aPWV in the gene profiling work.
approached significancep-value = 1.48 × 10 −4
The SZ_128 and SZ_342 features had no association, but the SZ_1M was higher in this subgroup compared to the other cases (Cohen’s d = 2.66) and could have approached significance (p-value = 1.48 × 10 −4 ) if not for the Bonferroni correction.
The difference between the decay profile of non-cuticular and cuticle characters is highly significant (Mann-Whitney-Wilcoxon p = 0.00018).
The dose and response exhibit a significant trend (at the 0.05 level) for both datasets (one-tailed Cochran-Armitage test 31 , n = 6 and P value = 1.91 × 10 −4 for DS1, n = 11 and P value = 1.11 × 10 −5 for DS2).
Moreover, multiple comparison analysis showed highly significant levels of β-III tubulin ( P = 0.0002), Nf-L ( P = 0.0403) and GFAP ( P < 0.015) in the subgroup of CSZ clozapine-treated.
However, the highly significant difference between the relative occurrence of bacterial families in ME and E lakes (ANOSIM r = 0.99, p = 0.0002) leads to the conclusion that the meso-eutrophic lakes were inhabited by different groups of bacteria than the eutrophic ones.
This caused a highly significant (p = 0.0002) decrease in OPC viability (Fig. 1h ).
We observed 192.7 nmol/100 mg tissue as the lowest value in the two experimental groups compared to a mean of 99.6 ± 42.3 nmol/100 mg tissue in the control group, resulting in a highly significant difference between control and experimental groups (p = 0.0002), see Fig. 1 A.
Instead, a highly significant main effect of the Cue Unpleasantness was found (F (1,16) = 23.33, P = 0.0002), reflecting higher unpleasantness ratings for identical (medium unpleasantness) stimuli when they followed a high rather than a low unpleasantness cue (see Fig. 2 and Table 1 ).
The difference between the cells infected with TTSuV1 and cells transfected with the unrelated DNA was highly significant at p = 0.0002 ( Fig. 2 ).
Moreover, linear regression analysis indeed indicated a highly significant (p = 0.0002) positive correlation between O -GlcNAc level and Akt phosphorylation in cervical tissues (Fig. 5 b).
This is also confirmed by the results of the ANOSIM test, wherein there was a strong and highly significant difference in assemblage composition among habitat alteration types (ANOSIM R = 0.759, P = 0.0002).
For females, this resulted in highly significant subspecies divergence in contact (t 55 = −4.19, P = 0.0002) but not allopatric samples (t 18 = −0.14, P = 0.89).
The correlation between the clock time estimate and clock time setting deviations was highly significant ( r =−0.88, p < 0.0002).
There were pathogenic deletion variants in 5.26% of females and 3.69% of males, and this difference was highly significant (P < 0.0002) ( Fig. 2B ).
Interestingly, our data revealed that a highly significant increase in myocilin expression (11.8-fold) was observed in TM region of the responder eyes compared to vehicle-treated eyes ( p = 0.0002); and there was a fourfold increase in myocilin expression in GC responder eyes ( p = 0.0004) compared with GC non-responder eyes.
3C–F ; the decrease was highly significant in the lung ( P = 0.0002) and almost achieved significance (p = 0.069) in the heart).
In contrast, hypertensive patients exhibited markedly higher concentrations, averaging 3.0 ± 0.7 ng/mL, and this difference was highly significant ( p = 0.0002).