The spine density per 100 μm of dendrite was 30.7 ± 3.7, compared to corresponding values of 15.9 ± 5.1 for the GRPR cells 18 , and this difference was highly significant ( P < 0.0001; t-test; Fig. 8 e).
Excerpts
Chemotype extract concentration also had a strong and highly significant effect on nematode motility (F = 20.44, p < 0.0001), demonstrating a clear dose-dependent response.
Temperature (T) and aging time (D) showed highly significant effects ( p < 0.0001), while humidity (H) also demonstrated a significant influence, with all three main factors falling below the 0.05 threshold.
communis had a highly significant effect on a wide range of bacterial groups independent of the watering regime as obtained with an analysis of differential abundance (ALDEx2) ( P < 0.0001) (Supplementary Figure S2 , S3 , Table S2 ).
In line with the above data, the PA14 AmiE + strain displayed a very strong and highly significant decrease in cytotoxicity ( P < 0.0001) ( Fig. 5C ).
Statistical analysis confirmed that the blue shifts in water absorption as temperature increased from 25 to 60 °C were highly significant ( P < 0.0001).
There was an extremely significant difference in the number of male offspring among the four crossings (SNK, P = 0.0001), though no significant difference was observed between (WT♀ × WT♂) (53.56 ± 2.49) and (TI♀ × TI♂) (58.35 ± 1.89) (SNK, P = 0.074), both of which gave approximately equal mean number of male and female progenies ( Table 1 ).
Pearl development kinetics Analyzing kinetics data over the 12 months of the study, we observed, as expected, a very highly significant difference in nacre thickness between harvest times ( p < 0.0001).
Statistical significance was set at p < 0.05, with p < 0.001 indicating a highly significant result and p < 0.0001with highest significant.
The interaction between current density and treatment time plays a decisive role in coating development, with a highly significant effect on hardness (IT = − 18.25, p < 0.0001).
Loss of p53 function produced a highly significant reduction in time to reach humane endpoints - median survival (Fig. 5D ; median 34.5 days vs 90 days; p < 0.0001).
The test revealed a highly significant effect ( P = 0.0001) of elevation on the community structure of mayflies, explaining 15.6% of the variance in species composition across the 31 sampled sites (Supplementary Table S2 ).
[ 4 b] gives: 8 which is a highly significant relationship ( p < 0,0001, see Fig. 4 ).
Note that MFI is displayed on a logarithmic scale, and the effect of all three anti-cytokine antibodies was highly significant (p < 0.0001) for IFN-γ.
As expected, highly significant differences were observed between different subgroups in relation to blood concentration (blood/feces p-< 0.0001, blood/mix p = 0.0155).
The model was highly significant ( P < 0.0001), with a coefficient of determination R 2 = 0.9937 and an adjusted R 2 = 0.9891.
All R 2 values were highly significant ( p < 0.0001).
The effect of masker frequency was highly significant, with F (6, 72) = 17.5, p < 0.0001, η p 2 = 0.59, and results are plotted in Fig. 3a as normalized suppression duration in a semilog plot.
Highly significant differences between pre- and post-weaning piglets were found ( P = 0.0001, P = 0.001 and P = 0.0001, for Envfit, Anosim and Adonis tests, respectively).
All inter-device correlations elicited a highly significant correlation with r-values of 0.72–0.86 (all p < 0.0001, Table 2 , Supplemental Figure S4).
Significance values are denoted by asterisks as defined by GraphPad Prism version 6.04: ****extremely significant (p < 0.0001); ***extremely significant (0.001 ≤ p ≤ 0.0001); **very significant (0.01 ≤ p ≤ 0.001); *significant (0.05 ≤ p ≤ 0.01).
Statistical analysis revealed that the differences in surfactin production across these carbon sources were highly significant ( p < 0.0001).
All these final selected variables showed a highly significant negative relationship with the infection rate (p < 0.0001; Tmin r = − 0.25, AP r = − 0.23, RH r = − 0.21).
Principal Curve scores show a positive relationship with chlorophyll a (representing the biomass of primary producers) ( edf = 2.8, P value < 0.0001) but negative with fucoxanthin, which is a proxy of diatoms, dinoflagellates, and chrysophytes ( edf = 4.03, P value < 0.0001), whereas in another model, the scores and alloxanthin, which is a proxy of cryptophytes, display a positive trend ( efd = 3.63, P value < 0.0001; Fig. 6 ).
However, the difference between both normal melanocytes and skin, as well as between tumor samples and skin, was not only highly significant (adjusted p -values < 0.0001) but also substantially larger in magnitude, as shown in Fig. 2 E.