Heterogeneity assessment and meta-analysis Highly significant heterogeneity was detected when all eligible studies were pooled (chi-squared = 35.73, I 2 = 72.0%, p<0.001).
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Results were considered significant if p<0.05, very significant if p<0.01 and extremely significant if p<0.001.
Similar to the results for promoter-proximal RNAPII peaks, we found a significant trend for genes with high 3′ end stalling indices to have lower levels of nucRNA and RNAPII coverage in the gene body (p<0.001, Jonckheere-Terpstra test, Figure 5B ).
The main effect of Group was highly significant, F (1,14) = 288,64; p < .001; η 2 = .95, due to the decrease in activity for those animals in the Paired as compared to those in the Unpaired Group.
A larger proportion of genes upregulated by alarm pheromone were upregulated in V+ bees, and a larger proportion of genes downregulated by alarm pheromone were downregulated in V+ bees; this distribution was highly significant (p<0.001, χ 2 = 11.21).
In the HR-HPV infection group, we found 844CT polymorphism in the HR-HPV-positive group had a more highly significant enrichment ( P <0.001, 0.500, respectively) than those in the HR-HPV-negative group.
We detected highly significant (even after Bonferroni correction) and positive linear contrasts for mtDNA/nDNA data (p = 0.001 and p = 0.023 for MGF and MGS, respectively).
Eight energy metabolism pathways (oxidative phosphorylation, citrate cycle, glycolysis/gluconeogenesis, pyruvate metabolism, pentose phosphate pathway, butanoate or propanoate metabolism, synthesis and degradation of ketone bodies, and fatty acid metabolism) and four amino acid metabolism pathways (arginine and proline, phenylalanine, tryptophan, and the aliphatic amino acids valine, leucine and isoleucine metabolisms) were identified, most of them at the three stages and highly significant ( p < 0.001; Table 2 ).
In most cases, the difference is highly significant (p<0.001).
Overall, survival proportions between larvae infected with the Δ argEF mutant strain or the Δ akuB strain are highly significant ( P < 0.001), which shows that the loss of ArgEF leads to reduced virulence in the G. mellonella infection model.
The comparison of the 1976 P2004 and 2003 P2004 samples revealed highly significant differences in flowering time (F 1,1806 = 19.6, P<0.001), plant height (F 1,1806 = 23.3, P<0.001) and spike length (F 1,1806 = 9.4, P≤0.002) between samples.
The association between PLR, NLR, MLR, SII and all-cause mortality and cardiovascular mortality The Kaplan–Meier curve revealed an increasing trend in long-term all-cause mortality and cardiovascular mortality rates with higher levels of PLR, NLR, MLR, and SII ( P < 0.001, Fig 3 – 4 ).
The dropping of Vra1 or Vra2 showed a highly significant reduction of the additive LOD (p<0.001 with F statistics).
The two-fold higher resistance to phosmet of females compared with males was highly significant (relative female:male potency = 1.99, t-value = 11.3, p-value < 0.001).
The number of eggs had a highly significant and positive correlation with the number of whitefly adults ( r = 0.857; P ≤ 0.001) landing on the leaf circles, indicating that the greater the number of whitefly adults, the more eggs were deposited.
Nearly all extracts showed a highly significant cell migration ( p < 0.001) across concentrations and time points, except for the 50 μg/mL methanol extract, which exhibited lower wound closure (52.4 ± 3.2%, p < 0.05).
DMR analysis did not find genome-wide significant regions, however 359 nominally significant candidate regions were identified, of which the top 10 regions had a nominal p-value <1.0 x 10 −3 ( S3 Table ).
Critically, the Category by SF scale was highly significant (F(2,28) = 9.48, MSE = 1.23, p <.001), implying a differential usage of SF information for the categorization of cars and airplanes in experts.
A highly significant difference in cAMP- and IP 3 baseline levels was detected at ZT 1, 9, 16, 18, 20, and 23 (Kruskal-Wallis test, p < 0.001).
majoris is known to decrease with age [42] , and age had a highly significant effect also in the present analysis (GLM (bird age) F 1,301 = 19.1, p<0.001, Figure 1 ).
For patient 28 the difference between the means for the 2 sides was highly significant (p<0.001 on Grubb’s test, and outside the outer fence on Tukey’s test), indicating that this patient was an outlier from the other patients in terms of side variation.
We observed a highly significant difference between the distributions of body color phenotypes among caterpillars raised on intact willow vs. intact birch ( Table 1, G = 745, P<0.001 ).
In that case, significant repression is observed (“D” females, 18% TSE; the difference with the level of E females is highly significant, χ 2 = 44.4, df = 1, p <10 −3 ).
The change in the difference between the inside and outside logger was highly significant ( F 2,49 = 10.75, P < 0.001) as evaluated using a general linear mixed model with a first-order autoregressive covariance structure to accommodate the covariance of measures taken at successive time intervals on the same trap.
In an ANOVA, the effect of continent (fixed) was not significant (F = 2.298; df = 1,8; P = 0.204); the effect of site (nested, random) was not significant (F = 1.224; df = 8,4; P = 0.424), but the effect of time (fixed) after application was highly significant ((F = 10.535; df = 4,160); P<0.001).