Excerpts

For incident CAD, the associated effect of rs4977574 was found to be highly significant in never-smokers (HR 1.26 per risk allele; 95% CI 1.13–1.40; P<0.001) and former smokers (HR = 1.20 per risk allele; 95% CI 1.08–1.32; P<0.001), whereas this associated effect was attenuated and not significant in current smokers (HR = 1.05 per risk allele; 95% CI 0.95–1.16; P = 0.326) ( Table 3 , Figure 2 ).

Although interaction between gender and aggression scores was highly significant [F = 10.991, p = 0.0010, η 2 = 0.014, power = 0.912], no gene-sex interaction was found (p = 0.8834).

The canonical correlations of the Discriminant Function Analysis were highly significant ( P < 0.001) and 94.8% of the cells were correctly reclassified in the resulting clusters.

Table 5 presents genome-wide significant and Figure 2 nominally significant results ( P <0.001) of a meta-analysis of the discovery sample and the replication sample.

A similar pattern of results was found for the measure of avoidance latency, with a highly significant two-way interaction, F (12,164) = 3.0, p = .001, reflecting poorer acquisition curves in the 50 and 100 Hz groups relative to the 20 Hz and no stimulation groups ( Figure 2 , middle panel).

All investigated genes showed highly significant sexually dimorphic expression in juvenile zebrafish gonads ( p <0.001).

The ANOVA found highly significant differences (p < 0.001) in leaf chlorophyll content between sites and canopy layers.

The model was highly significant [F (5,166) = 10.1; p<0.001] and predicted approximately 23% (R 2 ) of the variance in the outcome variable.

The association between PLR, NLR, MLR, SII and all-cause mortality and cardiovascular mortality The Kaplan–Meier curve revealed an increasing trend in long-term all-cause mortality and cardiovascular mortality rates with higher levels of PLR, NLR, MLR, and SII ( P < 0.001, Fig 3 – 4 ).

Critically, the Category by SF scale was highly significant (F(2,28) = 9.48, MSE = 1.23, p <.001), implying a differential usage of SF information for the categorization of cars and airplanes in experts.

Our results were consistent with a highly significant model ( Figure 3 ) (Boyce Index = 0.99; P<0.001) [27] .

Overall, survival proportions between larvae infected with the Δ argEF mutant strain or the Δ akuB strain are highly significant ( P < 0.001), which shows that the loss of ArgEF leads to reduced virulence in the G. mellonella infection model.

Differences were considered significant when p < .05(*), and very significant when p ≤ 0.01(**), and extremely significant when p ≤ 0,001(***).

A regression of SCR and 1⁄2MMDM (SCR = 0.07391 + 0.54761 * 1/2MMDM) ( Fig 2 ) was highly significant and predictive (p < 0.001, R 2 = 0.76, SE = 1.06, N = 53).

All pairwise comparisons among morphotypes from different localities resulted in a highly significant ( P < 0.001) genetic differentiation, with F ST values ranging from 0.971 (Cíes SU vs Arealonga RB) to 0.191 (Cíes SU vs Ons SU).

In the 100-item versions, highly significant inversion effects were evident on both our new tasks: Emotion-matching (upright: M = 77.59, SD = 7.64; inverted: M = 68.28, SD = 6.88; t (96) = 4.75, p <.001) and Emotion-labelling (upright: M = 83.10, SD = 6.87; inverted: M = 67.50, SD = 9.84; t (96) = 7.99, p <.001).

The Kaplan-Meier survival curves depicted in Fig 2 show a notable trend: participants diagnosed with either CKD or PAD had higher all-cause mortality and CCD mortality than participants without the corresponding two diseases (all P < 0.001).

There was a highly significant relationship between the average score of clinical competence and the participant’s age, sex, level of education, and years of clinical work experience ( P <0.001).

The results are highly significant for the entire shape ( F = 55.22; df = 1, 98; p < .001), the haft shape ( F = 26.95; df = 1, 98; p < .001), and the blade shape ( F = 69.67; df = 1, 98; p < .001), and we confidently reject the null hypothesis of “no allometry” (full results in S2 Table 1 in S2 Table ).

In 10 and 14 Gy animal groups, highly significant (p<0.001) body temperature decreases from 35 (± 3)°C to 28 (± 2)°C (20%) and to 22 (± 4)°C (40%) were observed 2 and 4 days, respectively, prior to death or euthanasia ( Fig 3C and 3D ).

There was a highly significant positive correlation between the density of T2R38-IR cells and BMI values (P = 0.001), but not between T2R38 mRNA levels and BMI ( Fig 2 ).

Dual luciferase activities were detected in different groups, with the results showing that, compared with the control group, dual luciferase activity in the treatment group was significantly reduced (by about 1.7 times), at extremely significant level ( P < 0.001, Fig 4B ).

This model had little explanatory power and a poor fit, as is common for bivariate logistic regression (McFadden’s Pseudo R 2 0.039, AUC 0.697, and a highly significant Hoslem’s test p<0.001).

The statistical analysis of mean difference of blue hole diameters from different H 2 O 2 showed that the increase of hole diameters is extremely significant (P<0.001) with the increase of H 2 O 2 from 0 to 20 mM, but not significant (P>0.05) with the increase of H 2 O 2 from 20 mM to 30 mM ( Table S1 ).

non-diabetic PC scores were highly significant (P<0.001 for both PC2 and PC3)(data not shown).