Barely Significant

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highly significantp<0.00010.0× alphaqualifiedgold
Assessment of total GIPR protein levels in both males and female mice reflected the mRNA findings and depicted a highly significant decline in expression from P7 to P21 ( Fig 2H and 2K , males p<0.0001, females p<0.0001). 2.5 Correlations of protein expression with glucose levels and body weight To determine a potential role or link between receptor expression in the hypothalamus and functions in physiology in development, we analyzed correlations between postnatal blood glucose and body weight in males and females combined.
highly significantp<0.00010.0× alphaqualifiedgold
The number of scales did not show significant differences among the four southern phenotypes (diagonal, vertical and longitudinal bars, and stellate spot; GLM: all p>0.4), whereas the difference was highly significant between these four phenotypes and the round spot skin pattern (GLM: t = 11.9, p<0.0001).
highly significantp<0.00010.0× alphaqualifiedgold
We found a highly significant association between signal in the DCR6 and escape bias overall (main effect of phenotype p<0.0001, with significant within-genotype effects after controlling for multiple comparisons in CaSR +/+ and CaSR p190/p190 groups) ( Fig 4A ).
showed a trendP<0.00010.0× alpha
On the other hand, the group of subjects who received PI vaccination showed a trend toward an increase in the median IgG titer (median values of 0.3 to 579 (P<0.0001), 0.00–401.4 (P = 0.3125), and 971.3 to 2163 (P = 0.3008) in group 1,2, and 3 respectively), except slight decrease of IgG value for Group 4 (median value of 1067 to 1021; P = 0.9717).
highly significantP<0.00010.0× alphaqualifiedgold
total and stage I+II ovarian cancer is highly significant (P<0.0001) but negligible for healthy vs. stages III+IV cancer (P = 0.043); in contrast for the more important differentiation between benign vs. ovarian cancer, the difference between CA125 and the panel is missing for benign vs. total and stage I+II ovarian cancer and rather better for benign vs. stage III+IV ovarian cancer (P = 0.045).
highly significantP <0.00010.0× alphaqualifiedgold
In fact, negative and highly significant Mantel correlation was observed for the DArT markers (−0.49, P <0.0001), confirming the presence of isolation-by-distance as the probable cause of the family structure found and once again justifying the inclusion of the K matrix in the association genetics analyses.
highly significantp = 0.00010.0× alphaqualifiedgold
The effects of the study drugs on gut microbiome β-diversity at the OTU level were first tested statistically using a two-way NPMANOVA and the results revealed highly significant main effects for drug (F 4,65 = 3.35; p = 0.0001) and time (F 2,65 = 8.43, p = 0.0001), as well as a significant interaction (F 8,65 = 1.77, p = 0.0001).
highly significantp -value<0.00010.0× alphaqualifiedgold
The hazard ratio in the Cox proportional hazards model is 2.619 (95% CI 1.733–3.956) with a highly significant p -value<0.0001, indicated that the ZingiVir-H treated group had a significant recovery period.
highly significantP <0.00010.0× alphaqualifiedgold
The onset of TAO within 2 years after the treatment with RAI and the titer of TSHR-Abs The relation between the onset of orbitopathy symptoms in patients with GD during a two-year of follow-up after a therapeutic dose of 131 I and the titer of TSHR-Abs in the serum was highly significant ( P <0.0001).