Adding calcium was associated with a highly significant reduction in SLS prevalence from about 60% without supplemented calcium to 15% in high and medium calcium-supplemented treatments (P < 0.0001, Fig 2 , Table 1 ).
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Assessment of total GIPR protein levels in both males and female mice reflected the mRNA findings and depicted a highly significant decline in expression from P7 to P21 ( Fig 2H and 2K , males p<0.0001, females p<0.0001). 2.5 Correlations of protein expression with glucose levels and body weight To determine a potential role or link between receptor expression in the hypothalamus and functions in physiology in development, we analyzed correlations between postnatal blood glucose and body weight in males and females combined.
The number of scales did not show significant differences among the four southern phenotypes (diagonal, vertical and longitudinal bars, and stellate spot; GLM: all p>0.4), whereas the difference was highly significant between these four phenotypes and the round spot skin pattern (GLM: t = 11.9, p<0.0001).
The results indicate that Group (ASD and the two TD groups) and Task (with and without objects) as main factors, are highly significant: (Group: F [2,75] 72,55 p<.0001; Task F [1,75] 220,52 p<.0001).
We found a highly significant association between signal in the DCR6 and escape bias overall (main effect of phenotype p<0.0001, with significant within-genotype effects after controlling for multiple comparisons in CaSR +/+ and CaSR p190/p190 groups) ( Fig 4A ).
= 1, p>0.35), but the interaction was highly significant (χ 2 = 20.86, d.f. = 1, p<0.0001).
The pattern of distribution for NM and M trials is almost mirror reversed, and consequently there is a highly significant difference when comparing the amount of original and reversed position trials for NM and M trials (χ 2 1 = 126.0, p<.0001, φ = .75).
Blood elevation of GST-π, DJ-1, NT-proBNP, NDKA and IL6 in stroke patients were highly significant ( p<.0001 ).
A highly significant increase in area under the ROC curve from ∼0.944 to >0.97 (p<0.0001) was noted upon addition of the ‘new’ tests and thereby established their positive impact on TBM diagnosis ( Figure 4 ).
showed a trendP<0.0001
On the other hand, the group of subjects who received PI vaccination showed a trend toward an increase in the median IgG titer (median values of 0.3 to 579 (P<0.0001), 0.00–401.4 (P = 0.3125), and 971.3 to 2163 (P = 0.3008) in group 1,2, and 3 respectively), except slight decrease of IgG value for Group 4 (median value of 1067 to 1021; P = 0.9717).
The model outputted a distribution of values with highly significant difference in their means (p < .0001) ( Fig 5 ).
total and stage I+II ovarian cancer is highly significant (P<0.0001) but negligible for healthy vs. stages III+IV cancer (P = 0.043); in contrast for the more important differentiation between benign vs. ovarian cancer, the difference between CA125 and the panel is missing for benign vs. total and stage I+II ovarian cancer and rather better for benign vs. stage III+IV ovarian cancer (P = 0.045).
Pairwise estimates of population differentiation were all high and highly significant ( Table 5 , P = 0.0001).
3b) , which is highly significant for CCL4 (p<0.0001, post test for linear trend).
A difference from global connectivity is that in this case the difference between healthy and control subjects is clearly significant (p-value < 0.0001).
( Table 3 ) An older age was a highly significant positive factor for abstinence (p<0.0001).
Furthermore, strain had highly significant effects on weight gain (p<0.0001), fat mass (p = 0.0002), and lean mass (p<0.0001), which did not interact with treatment ( Fig. 2A–E ).
In fact, negative and highly significant Mantel correlation was observed for the DArT markers (−0.49, P <0.0001), confirming the presence of isolation-by-distance as the probable cause of the family structure found and once again justifying the inclusion of the K matrix in the association genetics analyses.
The effects of the study drugs on gut microbiome β-diversity at the OTU level were first tested statistically using a two-way NPMANOVA and the results revealed highly significant main effects for drug (F 4,65 = 3.35; p = 0.0001) and time (F 2,65 = 8.43, p = 0.0001), as well as a significant interaction (F 8,65 = 1.77, p = 0.0001).
The hazard ratio in the Cox proportional hazards model is 2.619 (95% CI 1.733–3.956) with a highly significant p -value<0.0001, indicated that the ZingiVir-H treated group had a significant recovery period.
There were no significant differences with gender and there was a weak but highly significant positive correlation with age (Spearman rho = 0.205, p<0.0001).
The onset of TAO within 2 years after the treatment with RAI and the titer of TSHR-Abs The relation between the onset of orbitopathy symptoms in patients with GD during a two-year of follow-up after a therapeutic dose of 131 I and the titer of TSHR-Abs in the serum was highly significant ( P <0.0001).
All histologic parameters showed highly significant changes (each p<0.0001) 31 days postoperatively, except the irritation of the lamina elastica interna (p = 0.22).
Hence, the association of clade (C) with infections in horses is highly significant (p<0.0001; chi 2 test).
The backward logistic regression model ( Table 3 ) showed that the model was highly significant (p <0.0001, R squared 0.46).