Excerpts

Differences were highly significant in the chi-square test (P<0.0001).

The differences in the RODU of samples containing susceptible and resistant isolates were statistically highly significant ( p < 0.0001 {Mann-Whitney U test}).

Pelicans showed a trend (r 2 = 0.41, P<0.0001) toward earlier arrival between 1965 and 2008, with arrival dates advancing approximately 16 days ( Fig. 2 ; 21 April in 1965 vs. 5 April in 2008).

We found a highly significant positive correlation between the amount of C3d and BI in leprosy skin lesions (r = 0.9612, p<0.0001) ( Fig 7A ) .

Of the four SNPs with significant or borderline significant IL-2 associations in the whole blood assay, only rs10507173 was associated with CD4+ IL-2 production ( p <0.0001, general linearized model), though the association was driven by a single minor allele homozygote outlier (2H) and was not significant under a dominant model ( p = 0.95).

In contrast, a highly significant difference ( p <0.0001) was detected in the frequency of mspA phase ON (tract length of 6, 9 or 12Cs) strains in the carriage versus invasive collections ( Table 6 ), with mspA being significantly more often ON in invasive isolates compared to carriage isolates (69.2% compared to 50.0%).

Moreover, given that the microsatellite loci Tgu 9 and Indigo 41 are in highly significant LD ( P <0.0001) in all of the stocks despite being approximately 5 Mb apart, an immediately adjacent causative mutation would be expected to be in strong LD with the SNPs that we assayed within the MC1R .

japonicus was also highly significant (Fisher 2x2 exact test P<0.0001).

A highly significant relationship ( p <0.0001) was observed, with a plasma concentration of 355 ng/ml identified as that required for intracellular mycobacteriostasis.

A logistic linear model confirmed a highly significant effect of the treatment and genotype on the phenotypic sex, but not for the interaction term (treatment: p<0.0001; genotype: p<0.0025).

Contrary, the F ST between stocks was highly significant for both species, being 0.05677 for P. grosskopfii , and 0.10067 for P. yuma (P < 0.0001) ( Table 1 ).

Each term in the model (coverage, month, and region) was highly significant ( P < 0.0001) and provided significant explanatory power [ 16 ].

The differences in mean total tumor volume between the therapy and the placebo group were highly significant both on day 30 (therapy day 3) and 34 (therapy day 7; p<0.0001).

All LLR values were positive and the difference from zero was highly significant ( p <0.0001), indicating that the power law provided the better fit to the data.

Comparing all of the nine different chemical blends, there were highly significant differences (P<0.0001).

The difference between observed and expected distributions (both directions) was highly significant ( Chi 2 test, p<0.0001).

Tukey tests showed that this interaction was due to a substantial and highly significant right hemifield advantage for extrafoveal stimuli (left hemifield 57%, right hemifield 77%; p <0.0001) and no significant effect of hemifield for foveal stimuli (left hemifield 66%, right hemifield 65%, p >.50).

By 72 hours, a highly significant (p < 0.0001) significant reduction in p-AKT/AKT levels was noted across all treatment groups.

The difference in unique alleles between lines was 43,194 SNPs and highly significant ( P <0.0001).

The difference in tip extension rates between the two strains was highly significant (P value<0.0001, paired t -test).

As indicated in Fig 2C , the difference between malignant tissue and non-malignant paired tissue was highly significant ( p <0.0001), and the difference between malignant tissue and benign tumor tissue was significant ( p = 0.0115).

Consistent with the PCoA plots, clustering by reactors was highly significant (R = 0.65, p<0.0001).

Correlations of HOMA-IR HOMA-IR was highly significantly and positively correlated with hepatic triglyceride content (r:0.76;p<0.0001), and other less highly significant positive correlations were found with waist circumference (r:0.52;p<0.001), BMI (r:0.48;p<0.01), age (r:0.49;p<0.01) and serum ALT (r:0.3;p<0.03), while inverse correlation with serum adiponectin (r:0.47;p<0,01) and HDL-C (r:0.46;p<0.02) were observed.

Statistical analysis supported these findings: two-way repeated-measures ANOVA showed a highly significant treatment effect (p < 0.0001), with Dunnett’s post hoc tests revealing intense erythema and edema responses only in the positive control (MD 1.48–3.83, p < 0.0001), while Novostron did not differ from the negative control at any observation point.

156±29.6 pg/ml for T2DM and healthy controls, respectively), increase that is statistically highly significant (P<0.0001).