Barely Significant

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highly significantP-value < 0.00010.0× alphaqualifiedgold
We observed a highly significant correlation between genetic (Fst) and geographical distances (Mantel’s test, P-value < 0.0001, S3 Fig ) between populations (sites) of B. tabaci SSA1 SG1 U SG2 (this Mantel test was not performed on B. tabaci SG3 or SSA2 ∪ SSA3 due to low sample sizes).
highly significantP < 0.00010.0× alphaqualifiedgold
Construct validity of the 31-item Likert scale was supported by an overall Kaiser-Meyer-Olkin (KMO) measure of sampling adequacy (MSA) value of 0.853 (range 0.766 to 0.902), along with a highly significant Bartlett’s Test of Sphericity (P < 0.0001), indicating that the data were suitable for factor analysis ( Table 3 ).
a significant trendp < 0.00010.0× alphagold
Further, subgroup analysis based on the different assessments of IADL showed a significant trend toward higher difficulty in IADL in studies that used self-reported assessment (OR = 2.07, 95% CI 1.72–2.49, p < 0.0001, I 2 = 97%, p < 0.0001) compared with studies that objectively assessed IADL (OR = 1.60, 95% CI 1.28–2.00, p < 0.0001, I 2 = 81%, p < 0.0001) (test for subgroup difference: Chi 2 = 3.05, p = 0.08) ( Fig 13 ).
highly significantp<0.00010.0× alphaqualifiedgold
There was a highly significant positive correlation between hepatic cellular infiltrates and the copy number of dnTGFβRII transgene (r = 0.9342, p<0.0001), indicating that abrogation of TGFβ signaling by higher copy number of dnTGFβRII contributes to the emergence of T cell lymphoma-like T cell infiltration.