Barely Significant

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highly significantp<0.00010.0× alphaqualifiedgold
Cells expressing the control CYC1 3′UTR reporter showed little difference in the population mean fluorescence intensity (MFI) when Ssd1 was absent (0.87-fold change in expression in ssd1Δ compared to SSD1 ), while cells containing the test CTS1 3′UTR construct exhibited a nearly three-fold, highly significant increase (p<0.0001) in MFI in ssd1Δ cells compared to SSD1 cells ( Figure S1A ).
a significant trendp < 0.00010.0× alphagold
Further, subgroup analysis based on the different assessments of IADL showed a significant trend toward higher difficulty in IADL in studies that used self-reported assessment (OR = 2.07, 95% CI 1.72–2.49, p < 0.0001, I 2 = 97%, p < 0.0001) compared with studies that objectively assessed IADL (OR = 1.60, 95% CI 1.28–2.00, p < 0.0001, I 2 = 81%, p < 0.0001) (test for subgroup difference: Chi 2 = 3.05, p = 0.08) ( Fig 13 ).
highly significantP-value < 0.00010.0× alphaqualifiedgold
We observed a highly significant correlation between genetic (Fst) and geographical distances (Mantel’s test, P-value < 0.0001, S3 Fig ) between populations (sites) of B. tabaci SSA1 SG1 U SG2 (this Mantel test was not performed on B. tabaci SG3 or SSA2 ∪ SSA3 due to low sample sizes).