Excerpts

The difference was highly significant ( P = 1.28x10 -6 ).

SNP associations were genome-wide significant with CC-BNT (P<2.4×10 −7 ) and CC-WRAT (P<1.0×10 −8 ), nearly genome wide significant with CC-LMI (P<6.0×10 −7 ), and highly significant with CC-LMD (P<1.3×10 −6 ), CC-HVOT (P<1.9×10 −6 ) and CC-TMTB (P<3.7×10 −6 ).

However, there was a highly significant difference in rank changes between the MSR and FSM management regimes (P = 0.00000132, Welch’s T Test, Two-tailed).

BMI is also strongly correlated with SES ( Figure 2 ) but the association of BMI with disease remains highly significant even after accounting for SES and ancestry ( c BMI = 0.09241, P = 1.34 × 10 −6 ).

Unlike our highly significant findings, where adjusted R2=0.610 and p= 1.45E-06, Kumar et al “did not observe the statistically significant association of mean temperature and spread of the COVID-19” (6). c.

The main, highly significant finding of our study was that lactate (Discovery group: p<1.6x10 -6 , q = 0.00; Test group: p = 0.003; q = 0.047) and pyruvate (Discovery group: p = 0.017, q = 0.27; Test group: p = 0.010, q = 0.10), two products of anaerobic respiration in glycolysis, were significantly elevated in the PTSD-positive subjects compared to the PTSD negative subjects.

However, this SNP was only borderline significant in the Norwegian sample (p-value = 1.8 × 10 − 6 ).

This difference between normal and tumor tissue was highly significant (p-value = 2*10 −6 ).

The corresponding rm-ANOVA (3 face conditions×14 ROIs) showed highly significant effects of Face condition (F(2,18) = 30.4, p<0.000002, H-F epsilon = 0.997, p<0.000002), and ROI (F(13,117) = 4.44, H-F epsilon = 0.26, p<0.008), and a significant interaction between these two factors (F(26,234) = 2, p<0.005, H-F epsilon = 0.5, p<0.03).

The difference in differentially expressed mature miRNAs in the 22q11.2 del region that showed nominally significant differences in expression compared with mature miRNAs generated from the remainder of miRNA genes on chromosome 22 is highly significant (Fisher exact test, p = 2E-06).

Reagents based on CPPs (Proteoducin, Chariot) showed a particularly strong and highly significant (p = 2.03*10 −6 and p = 5.20*10 −7 ) cytosolic distribution after PCI treatment.

Twenty-six SNPs (11 non-synonymous and 14 synonymous) showed statistically significant differences (P<0.05), and two SNPs, in position 1039 and 1041 of cagE , showed a highly significant association with cancer (p-value = 2.07×10 −6 ), and the variant codon was located in the VirB3 homology domain of Agrobacterium .

Detailed analysis identified a total of 524 highly significant MTAs (pvalue >2.1×10–6) with wide phenotypic variance (PV) range (5.81–90.09%) for 36 traits.

As this test was extremely significant (p-value = 2.2*10 −6 ), we rejected the null hypothesis and assessed the effect of the partial smoke-free legislation on AMI incidence, mortality, and case-fatality by negative binomial regression analysis.

At a minimum length of 3 Mb, the rate in cases and controls dropped to 0.65 and 0.52, respectively, indicating a highly significant excess of homozygosity in cases (ratio: 1.25, p = 2.30×10 −6 ).

Strikingly, Pita program [39] predicted a highly significant global miRNA binding preference to the reference genomic sequence over the mutated sequence (p = 2.5×10 −6 ) in the melanoma patient genome, independently of the exact ΔΔG threshold chosen to define binding ( Figure 1A ).

Parameters are statistically highly significant ( r = 0.9712 and p = 0.000003) while analysis of residual distribution shows a good agreement with the normal distribution (Shapiro-Wilk test, W = 0.9608, p = 0.7952).

Conversely, the recA generalized linear model showed little difference to the null model ( p -value = 0.93), whereas that of pstS showed a highly significant difference ( p -value = 3.08×10 −6 ) from the null model ( Figure 4 ).

While differences between normal aging and AMD were not significant, the percentage of CD34 negative capillaries in old eyes, compared to young eyes, was highly significant (p = 3.8×10 −6 ).

This is exemplified by the highly significant difference in PPA activity in no-blink vs. blink trials (t(23) = 5.97; p = 4.4*10-6), listed below.

Looking first at the conservative simple Reference Range Plus method, the analysis found a highly significant genotype effect as a high proportion of the rats were classified as low ( Table 2 ) (male dataset, p value = 4.75e-6 with a 43% change in classification and female dataset p value = 4.64e-3 with a 26% change in classification).

Time-wise comparisons were all highly significant ( p = 5×10 −6 *, each based on 8 replicate experiments).

The overlap between ME3 and an aging methylation module found in solid tissues is also highly significant (Fisher-exact p=5.6 x 10 -6 , odds ratio=1.91).

The difference in filopodia numbers was significant between paired data sets showing low and high red-to-green pixel intensity ratios ( t s = 4.13, p = 0.00029), highly significant between data sets showing low and high red pixel intensity ( t s = 5.72, p = 0.000006,) and not significant between data sets showing low and high green pixel intensity ( t s = 1.29, p = 0.207).

The Device-On group, who used the EyeMusic with minimal training were easily able to complete all three parts of the task, with a highly significant success rate of 95.1±8.1% (p<6.3*10^ -6 in comparison to the Device-Off group) for recognition of which door was different, 89.7±11.9% (p<1.1*10^ -5 in comparison to the Device-Off group) for correctly explaining how it was different, and 89.5±13% (p<9.8*10^ -6 in comparison to the Device-Off group) for navigating correctly to the exit (See Fig 5 ).