Excerpts

Comparing CYP26B1 negative and weakly positive tumours with CYP26B1 moderate and strong expressing tumours showed that there was a highly significant association with survival (HR = 1.465, 95%CI = 1.151–1.865, χ 2 = 9.832, p = 0.002).

Although the number of cells did not decrease to the levels found in control non-sensitized animals, the decrease was dose proportional and highly significant (p < 0.002) when compared to OVA-sensitized mice which did not receive ASM-024.

The prolonged implant survival for the membrane-group is highly significant (p=0.002).

The effect of DNMT3A genotype on birth weight and DNMT3B on length of gestation were the least significant before the exclusion and just below significance following the reduction in numbers; though the stronger DNMT3B effect on risk of prematurity remained highly significant (p = 0.002) after exclusion of the non-Caucasian pregnancies.

However, at the end of the intervention, a highly significant difference could be noted between the groups, with a higher score in the active treatment group (t = 3.11; P = 0.002).

Splitting the analysis by gender consequently gave a highly significant association for women [χ 2 (1) = 10.71, p = 0.002] but not for men [χ 2 (1) = 0.052, p<1.00].

The differences in mean homoarginine concentrations across the stages of CKD were highly significant (p = 0.002).

Comparison of the frequency of amplification among these three groups is highly significant with p = 0.0020 and 0.0011, comparing the first group with each of the second two groups (Fisher's exact test).

Each of the miRNA and mRNA interactions were highly significant among 7 of the 8 miRNAs identified (p-value = 0.002 to 0.008).

There was highly significant genotypic differentiation (Fisher's exact test = P<0.002, df = 14) within populations for all loci except Dicten18 and Dicten27 (Fisher's exact test = P>0.1, df = 14).

In the “response to stress” genes, the enrichment of contacts is also highly significant (number of genes = 561, ratio = 1.43 and p-value = 2×10 −3 ).

Genetic structure analyses revealed significant differences in haplotype frequencies among haplotypes resulting in a highly significant fixation index ( F ST = 0.0296, p = 0.002).

In the primary analysis, the ex vivo TNF-α values showed different temporal dynamics than the in vivo values as indicated by a highly significant group by time interaction analysis comparing the ex vivo and the in vivo values after the TNF-α peak, i.e. from 3 to 24 h (p = 0.002).

Additionally, both cytokines showed a trend towards an association with disease severity (rho = 0.310, P = 0.002; rho = 0.188, P = 0.059, for IL-6 and IL-8, respectively).

Zeta-potential decrease was observed for these proteoliposomes as well, and in comparison with control liposomes proved to be highly significant ( Figure 3E ; n = 5, p = 0.002).

Our array contained 27 SNPs in the vicinity, and only one, namely rs4131943, had a nominally significant association with influenza A severity (p = 2.1×10 −3 , OR = 2.60 95% CI 1.40–4.83); note that the hypothesis-specific number of tests was 27, and that the multiple testing correction would yield p = 0.0567.

In contrast to fruits dried at 100°C, storage time on cuA and cuB from fruits dried at 52°C was highly significant (p ≤ 0.0021), under tropical conditions contributing 89 and 95% in total treatment variation (TTV) of the respective variables.

Protection in the 8 h group was highly significant vs CG (p = 0.0022 Fig. 4C ), and the 47% protection after 24 h approached but did not reach significance (p = 0.0566) ( Table 3 ).

This effect was accompanied by a highly significant increase in mobility of α7-nAChRs residing on dendrites (from 0.018±0.024 to 0.025±0.027 μm 2 /s; t = 5.015 df = 1352, p = 0.0023) whereas axonal QDs exhibited a moderate reduction in mobility (from 0.218±0.104 to 0.187±0.04 μm 2 /s; t = 2.811 df = 289, p = 0.0103) ( Fig. 6A ).

A statistical trend was observed for P3 latency and the EDSS variable, r = 0.638, p = 0.0024).

Despite the low number of cases and non-estimable data, a highly significant ( p = 0.0024) relationship between the BG and the time to relapse for VC was found.

A 2-way ANOVA on condition and Δf confirmed that the bias showed a significant effect of condition (LFP: F(5,1735) = 31, p∼0; MUA: F(5,615) = 12,p∼0), a non-significant main effect of Δf (LFP: F(3,1735) = 0.99, n.s.; MUA: F(3,615) = 0.95, n.s.), but a highly significant interaction between condition and Δf (LFP: F(15,1735) = 4.9, p∼0; MUA: F(15,615) = 2.38, p = 0.0024).

It is worth to bring to mind that in a larger dataset of 34 teleostean species the correlation between MR and GCg was highly significant, p -value<2.5×10 −3 [24] .

For histopathological data, the levels of significance were defined as: 0.0025< P ≤0.0125: * (slightly significant); 0.00025< P ≤0.0025: ** (significant); P ≤0.00025: *** (highly significant).

Subsequent statistical analysis (general linear model) revealed highly significant variations between trials for control lines of the circulating system ( p = 0.0025).