In addition, similar and all highly significant ( p ≤ 3.9 × 10 −4 ) Pearson correlations were found between all three housekeeping genes; GAPDH, HBB, and ACTB, for all collection volumes ( Figure A3 ).
Excerpts
The interaction between AgNO 3 concentration and temperature (AD) was highly significant ( p = 0.0007, F = 16.35), suggesting a strong combined effect on ZP.
For TPC, the quadratic model was highly significant (F = 32.20, p = 0.0007; Table 2 ), indicating that the model adequately describes the relationship between extraction variables and phenolic recovery.
The highest level was observed in the 40% combination group (CDDP 11.2 μM + ε-VNF 8.4 μM), reaching 4.3 ± 0.6 μM, which was found to be highly significant (*** p < 0.001).
Although the water volume (X 2 ) shows no significant linear effect on the benzoate concentration ( p = 0.810), the highly significant quadratic term (X 2 2 ; F = 19.63, p = 0.001) implies the existence of an optimal level for this parameter within the experimental range.
On the contrary, magnesium oxide showed a marked and highly significant destabilizing effect, in particular, in the accelerated test conditions ( p < 0.001).
Each group was individually compared with the positive control and the statistical differences were shown, as follows: *: significant ( p < 0.05); **: highly significant ( p < 0.01); ***: extremely significant ( p < 0.001); and, ns: non-significant ( p > 0.05).
Glibenclamide (10 mg/kg) exhibited highly significant ( p < 0.001) hypoglycemic effects throughout the study period.
Although there was a weak trend (y = 0.23x − 142.1, p < 0.001) showing increased difference between the two methods ( Figure 7 c), this increase in difference is of small practical importance and in most cases the error will be smaller than the analytical precision.
Direct comparison between AMO and AMOR revealed highly significant differences for both cytokines ( p < 0.001 for IL-1β and p < 0.01 for IL-6), confirming the superior anti-inflammatory efficacy of AMOR in this model.
After post-hoc testing, the following significance levels were specified: extremely significant ( p < 0.001; ***/+++/###, very significant ( p < 0.01; **/++/##), significant ( p < 0.05; */+/#), and not significant ( p > 0.05).
As shown in Figure 3 and Table 3 , the p -value of each model term indicated that the quadratic terms of X 2 2 and X 3 2 have highly significant effects with T P and T F ( p < 0.001), which indicated the important role of extraction time and liquid-to-solid ratio on content.
thermophilus across all treatments and declined systematically during storage, which was confirmed by highly significant effects of SCGL concentration ( p < 0.001, η 2 p = 0.994), time ( p < 0.001, η 2 p = 0.890) and their interaction ( p < 0.001, η 2 p = 0.976) ( Figure 1 ).
There was also a highly significant statistical difference between the analyzed extracts in this system ( p < 0.001).
Not surprisingly, this correlogram showed a strong and highly significant ( p < 0.001) correlation between silymarin content and the in vitro antioxidant assays CUPRAC (PCC = 0.92) and FRAP (PCC = 0.91).
The coefficients of X 3 , X 1 X 2 , X 2 X 3 , X 1 2 , X 2 2 , and X 3 2 were highly significant ( p < 0.001), while those of X 1 and X 2 were statistically significant ( p < 0.01).
The cross validation of the model using CV-ANOVA provided highly significant results (F = 10.3017, p < 0.001).
Average sulfur (S) contents were low (0.20% to 0.05%), but differences between sites were also highly significant ( p < 0.001), following essentially the same sequence as C content.
Specifically, the sampling period exerted a highly significant ( p < 0.001) main effect on the extracts, density, and refractive index ( Table 2 ).
In this line, the contractile response to PE was tested and both compounds significantly reduced the contractile response to PE, although oxime–1 showed a more highly significant ( p < 0.001) reduction of the contractile response to different concentrations of PE (10 −7 to 10 −5 M).
All the obtained values were statistically highly significant ( p < 0.001).
The fractionated PC also showed a considerably significant ( p < 0.001) prooxidant effect in conjunction with UVA exposure on keratinocytes.
p < 0.05 indicates a significant difference, p < 0.01 indicates a highly significant difference, and p < 0.001 indicates a highly significant difference. 4.
Highly significant correlation was observed between TPC and TFC (r = 0.973, ( p < 0.001).
A highly significant main effect was observed for the geographical origin of propolis (Country; F = 91.27, p < 0.001).