Meanwhile, a non-significant value of lack of fit ( p > 0.05) and a highly significant level of the model ( p < 0.01) were obtained by statistical analyses, suggesting that the mode could be accurately predicted by the variation [ 38 ].
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Specifically, two linear ( X 2 and X 3 ) and two quadratics ( X 2 2 and X 3 2 ) were highly significant model terms ( p < 0.01).
The results showed that the regression model of ZJRP yield was highly significant ( P < 0.01).
[ 27 ] proposed that Na, Mg, Ca, Cr, Fe Ni, Rb, Sr, Cd, Tl, and Pb were extremely significant correlated between tea leaves and topsoil at the level of p < 0.01.
Nevertheless, oral administration of ECE at 800 mg/kg ( Figure 1 b; D + E8) caused significant declines of the fasting blood glucose compared to those of the DC rats at the correspondingly same day from the 2nd to the 7th day ( p < 0.05) and extremely significant decreases since the 10th day ( p < 0.01).
After administration of the RA pretreatment, hepatic and renal IL-1β, IL-6, and TNF-α mRNA expression levels showed a significant downregulation ( p < 0.01) and SOD, CAT, and GPx mRNA expression levels showed a highly significant upregulation ( p < 0.01) compared to CP induction alone.
Effects of ACP-60-A, ACP-60-B and ACP-60-C on HK-2 Cell Viability As shown in Figure 11 , the survival rate of HK-2 cells in the Mod group significantly decreased compared to the Con group, indicating a highly significant difference ( p < 0.01).
Differences were considered highly significant when p < 0.01.
Total Phenolic Content (TPC) A highly significant effect of cultivar on the TPC ( p < 0.01) was established, with the R0 wine exhibiting a 45% higher content of phenolic compounds compared to J0 ( Figure 1 , Table S2 ).
On the other hand, there was a highly significant reduction in tumour volume ratio after a single Au-GSH-Dox injection ( p < 0.01) ( Figure 1 and Figure 2 ).
However, the quadratic effect ( X 1 2 , X 2 2 , X 3 2 ) was found to produce extremely significant ( p < 0.01) positive effect on both Y 1 and Y 2 , but X 4 2 was only significant for Y 2 .
Statistical differences were considered significant when p < 0.05 (*) and highly significant when p < 0.01 (**) and p < 0.001 (***). 5.
The analysis of variance showed that this regression model was highly significant (P < 0.01) with an F- value of 198.23, implying a good fit between the predicted model and the experimental data.
Pairwise comparisons revealed that the increase from 50 to 100 μg/mL was highly significant ( p < 0.01), while further increases from 100 to 200 μg/mL and from 200 to 300 μg/mL remained statistically significant ( p < 0.05).
Highly significant differences (P ≤ 0.01) were observed among the different doses of irradiation.
The determination criteria were the following: R 2 of the fitted 4-parameter curve of ≥0.98, regression item should be highly significant ( p < 0.01), and deviation from parallel should not be significant ( p ≥ 0.01).
The statistical significance was set up p < 0.05, highly significant p < 0.01.
Compared with the CDP group, the C max of CA increased significantly ( p < 0.05), and V z/F of CA had a highly significant rise in the JGL group ( p < 0.01), but there was no significant difference in the AUC and MRT between the two groups.
rusticana root oil and the negative control was highly significant ( p < 0.01) for doses greater than 0.025 mg/cm 2 .
The ANOVA showed that the influence of treatment on colour, flavour, and texture was non-significant ( p > 0.05); however, a highly significant ( p ≤ 0.01) influence was observed on taste.
The following p -values were categorized and interpreted as statistically significant: 0.01 ≤ p < 0.05: Significant ( p < 0.05); 0.001 ≤ p < 0.01: Highly significant ( p < 0.01); p < 0.001: Extremely significant ( p < 0.001).
The results showed that STZ-diabetic rats exhibited a highly significant decrease in serum GSH levels relative to healthy controls ( p < 0.01), while those in groups treated with every concentration of both RR and BR showed a marked elevation relative to untreated diabetic rats ( p < 0.05) ( Figure 4 A).
Subsequent analysis of variance (ANOVA, Table 3 ) corroborates these findings, demonstrating that ultrasonic power is a highly significant factor ( p < 0.01), while material-to-liquid ratio and extraction time are statistically significant ( p < 0.05).
Specifically, the linear effect of X 1 , X 2 and X 4 illustrated highly significant ( p < 0.01) and remarkably significant ( p < 0.001) positive effects on FRAP, respectively, while their square terms (X 1 2 , X 2 2 and X 4 2 ) exhibited highly significant ( p < 0.01), significant ( p < 0.05) and remarkably significant ( p < 0.001) negative ones, respectively.
On the contrary, blackcurrant had a highly significant influence on the five vineyards with a 99% confidence level ( p < 0.01) that means blackcurrant made a very different contribution among these vineyards.