Postmenstrual bleeding showed a highly significant difference, occurring in 47.0% of patients with isthmocele versus 4.7% of those without ( p < 0.001).
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Age itself showed a strong, highly significant negative association with DMFT in all models ( β around −1.1, p < 0.001), indicating that, within this caries group, younger children tended to have higher DMFT scores.
In the RMS model, total RMS was not associated with BCVA (β ≈ 0.00 logMAR per μm, p = 0.997), whereas the time effect remained highly significant (β ≈ −0.97, p = 0.001).
Similarly, for the detection of non-growing rod systems, GPT-4o exhibited near-perfect sensitivity (M = 0.98, SE = 0.00), significantly surpassing BiomedClip (M = 0.23, SE = 0.02), as reflected in a highly significant statistical difference (z = 37.5, p < 0.001).
Living donor type exhibited a highly significant ( p < 0.001) positive impact on the time to graft failure.
Differences were found mainly between the control and periodontitis groups: highly significant differences in species load were detected in C. rectus, T. forsythia, and P. gingivalis ( p -value ≤ 0.001), followed by S. mutans and F. nucleatum ( p -value = 0.05–0.001), as well as T. denticola , P. intermedia , and oral Lactobacilli ( p -value = 0.01–0.05).
Bartlett’s Test of Sphericity was highly significant (χ 2 = 186, df = 15, p < 0.001), confirming that the correlation matrix differed significantly from an identity matrix and that the variables were sufficiently intercorrelated for PCA.
Mean serum cTnT concentrations showed an increasing trend during the run, with a significant difference between 24-h run compared to concentration at baseline ( p < 0.001), marathon ( p < 0.001) and 12-h run ( p < 0.01) ( Figure 3 ).
In an overall analysis, a highly significant correlation of VASp with movement restriction (MR) ( p -value ≤ 0.001), the presence of joint effusion ( p -value ≤ 0.001), and the diagnosis of RA ( p -value ≤ 0.001) were observed.
Based on log2 relative expression, of the samples that demonstrated low expression levels (62%),45% were highly significant *** ( p = 0.001),5%were significant ** ( p < 0.05) and 5% showed less significance * ( p < 0.05) while the rest of the (15%) samples were non-significant ( p > 0.05).
The use of SGLT-2 inhibitors showed a highly significant association with lower HF incidence ( p < 0.001) ( Table 2 ).
In both groups, aortic stenosis was successfully treated, as reflected by highly significant decreases of Vmax, dpmax and dpmean ( p < 0.001).
Within-group analysis showed the IG achieved highly significant longitudinal improvements in pain and psychological discomfort (all p < 0.001).
Nevertheless, the combined effect of the predictors on the independent variables was highly significant (η 2 = 0.883; p < 0.001), and thus the null hypothesis of the investigation can be rejected.
This reduction was statistically highly significant ( p = 0.001).
In addition, reduced (≤2.0) coronary flow reserve (CFR) determined using 2D echocardiography in patients with diabetes and negative dipyridamole stress echocardiography carries highly significant and convincing worse outcome in comparison with preserved CFR (>2.0) over a follow-up of 3 years (58% vs. 16%, p < 0.001) [ 27 ].
Alternative analysis by comparison of individual vessel size for each tissue type was highly significant ( Supplementary Figure S1A ) and analysis of vessel density showed a 2.4-fold increase in the number of vessels per field in NU compared with IP tissue ( p = 0.001, Figure 3 A).
The incorporation of first visit information led to a decrease in AIC (Akaike Information Criteria) that was highly significant ( p < 0.001) compared to the model using baseline data alone.
For RCII, the association was stronger and more consistent: per SD increase (OR 1.23, 95% CI: 1.00–1.51, p = 0.046) and Q4 (OR 5.20, 95% CI: 2.24–12.08, p < 0.001) both showed significant independent associations, with a significant trend across quartiles ( p < 0.001).
Model 3 (AHEAD): When the AHEAD score was included, it emerged as a powerful and highly significant predictor of heart failure (OR = 1.786, 95% CI: 1.522–2.097, p < 0.001).
However, when considering all 2700 implants, the association of corticalization with marginal bone loss is statistically highly significant ( p < 0.001).
The transformation also altered the apparent significance of individual predictors: the ST/HR index, which appeared highly significant in untransformed models ( p < 0.001), lost significance after log transformation ( p = 0.501), whereas HRR at 1 min became significant ( p < 0.001).
Bilateral gonial angles demonstrated strong symmetry, with a highly significant positive correlation (r = 0.795, 95% CI 0.695–0.864, p < 0.001).
In the CALLY analysis, the low-CALLY group had a markedly shorter median survival (20.1 months, 95% CI: 20.1–56.7) compared with the high-CALLY group (89.0 months, 95% CI: 89.0–111.3), with a highly significant difference (log-rank p < 0.001).
reported remission of NAFLD in 56% of patients undergoing VSG, with a highly significant association between NAFLD remission and achieving greater than 50% excess weight loss (odds ratio 10.1, p < 0.001), further stressing the relationship between effective weight loss and liver disease resolution [ 38 ].