Real-World Evaluation of the HELPP Score and CALLY Index for Preoperative Prognostic Stratification in Resectable Pancreatic Ductal Adenocarcinoma.

J Clin Med · 2025 · PMC12786992 · PMID 41517561

Europe PMC DOI

hedged sentences

0.0010

closest p · 0.0× alpha

0.0520

boldest claim

The sentences

highly significantp < 0.001actually significant

In the CALLY analysis, the low-CALLY group had a markedly shorter median survival (20.1 months, 95% CI: 20.1–56.7) compared with the high-CALLY group (89.0 months, 95% CI: 89.0–111.3), with a highly significant difference (log-rank p < 0.001).

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narrowly missed statistical significancep = 0.052so close (0.05 < p ≤ 0.1)

In our pancreatic cancer cohort, although a CALLY score ≤ 1.029 was significantly correlated with shorter OS and DFS in Kaplan–Meier analysis, it narrowly missed statistical significance in multivariate regression (HR: 3.535, p = 0.052).

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did not reach statistical significanceno p-value reported

In multivariate analysis, the HELPP score was identified as an independent predictor of survival, whereas the CALLY index, although associated with survival in univariate analysis, did not reach statistical significance.

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