Excerpts

The linear term and quadratic term were highly significant ( P < 0.01).

In both L-CSL groups, the mRNA levels of Nrf2 and Nqo1 were significantly higher than those in the SHR group ( p ≤ 0.01), with a highly significant difference between the two CSL doses ( p ≤ 0.01).

Our results revealed an increasing trend in n -3 and n -6 LCPUFA and a marked increase in C18:0, C20:4 n -6, C22:6 n -3 ( p < 0.01) and C22:5 n -3 ( p < 0.05), respectively ( Figure 6 ). 3.

In terms of inflammatory and oxidative stress markers, L-proline and 9(S)-HODE both showed highly significant correlations with ATP levels ( p < 0.01) and moderate associations with IL-1β ( p < 0.05).

However, compilation of the results ( Figure 6 ) shows that the increase in nucleoplasmic resting ROS induced by the ETB receptor antagonist is highly significant ( Figure 6 C, p < 0.01), without further increases in whole-cell and cytosolic resting levels of ROS ( Figure 6 A,B). 2.2.

Differences were considered statistically significant at p < 0.05, and highly significant at p < 0.01.

Statistical significance of observed differences was determined by analysis of variance (ANOVA), where * indicates significant differences ( p < 0.05) and ** denotes highly significant differences ( p < 0.01). 5.

In contrast, miR-202-5p expression in TCs showed a trend of first decreasing and then increasing from pre-hierarchical follicles 4–6 mm and 8–10 mm, to hierarchical follicles F5, F2–4, and F1, and, apart from the highly significant difference in changes observed between 8 and 10 mm pre-hierarchical follicles and F5 hierarchical follicles ( p < 0.01), changes at other stages did not show a significant differences ( p > 0.05) ( Figure 1 D).

When the concentration was greater than or equal to 1/2MIC, the anti-microbial peptide Citrocin showed highly significant ( p < 0.01) biofilm inhibition of P. aeruginosa .

For all assays, differences between samples or time points were regarded as significant if p ≤ 0.05 and highly significant if p ≤ 0.01.

There were highly significant differences between Hap 1 and Hap 2/Hap 3 at p < 0.01, and there were no significant differences between Hap 2 and Hap 3 ( Figure 3 D).

The statistical analyses indicate that the overexpression was highly significant, with p < 0.01 vs. control for samples treated with 25 μM Aβ 25–35 peptide and with p < 0.001 vs. control for samples treated with EtOAc extract or with both Aβ 25–35 peptide and EtOAc extract.

CS elevated DCF fluorescence approximately 3.5 times ( p < 0.01), while ECA exposure resulted in smaller but highly significant values, reaching about 2–2.5 times higher ( p < 0.01) fluorescence. 2.2.2.

A series of highly significant correlations (r s = 1.000, p < 0.01) were identified among Otx2 protein levels across multiple ocular tissues, including the lens, optic nerve, ciliary body, iris, sclera, and eyelid.

The expression of EDA was examined at different time points of PEDV infection, and the results showed that the EDA gene showed a highly significant upregulated expression at 24 h and 48 h ( p < 0.01) ( Figure 2 B).

The results showed a highly significant correlation between sphingolipid metabolism and key metabolites in pyrimidine metabolism ( p < 0.01, Figure S3 ).

Notably, Spearman correlation analysis revealed a highly significant negative correlation between FS and LP within the population (r = −0.37, p < 0.01) ( Figure 2 c).

All six time points show p -values below 0.05, with most comparisons demonstrating highly significant differences ( p < 0.01, Figure 3 B).

Different letters indicate significant differences at p < 0.05 and extremely significant differences at p < 0.01.

The interaction of different lines and water status has a highly significant effect on CC, LA, PH, NNMS, BN, RWCL, and BIOMASS ( p < 0.01), a significant effect on SWPP ( p < 0.05), and no significant effect on the trait RECL. 2.2.

Indeed, patients with LEP overexpression had a strong trend toward better prognosis marked by lower recurrence (DFS; log-rank p = 0.01; Figure 2 ) and reduced disease-specific deaths (DSS, log-rank p = 0.002; Figure 3 ).

The activity of TPH1-1325T was five times higher than that of TPH1-1325C, and their difference was highly significant ( p < 0.01). 3.

The impact of depth was particularly pronounced for indel calling, as evidenced by both highly significant p -values ( p < 0.01) and substantially larger effect size estimates compared to those observed for SNV calling.

Statistically, “**” indicates highly significant differences ( p < 0.01), “*” indicates significant differences ( p < 0.05), and “N.S.” indicates non-significant differences ( p > 0.05). 5.

Differential expression of CD58, CD304, and CD73 in diagnostic samples was highly significant ( p < 0.01) between pre-B-I, pre-B-II, immature B cells, and BCP-ALL blasts.