Barely Significant

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highly significantp = 0.0010.0× alphaqualifiedgold
The subsequent PERMANOVA confirmed very strong, highly significant metabolic shifts comparing predose and postdose metabolomics signatures with F = 20.665, R 2 = 0.408, p = 0.001 for visit 2 and with F = 16.084, R 2 = 0.349, p = 0.001 for visit 1, based on 999 permutations in both analysis cases.
extremely significantp < 0.0010.0× alphaqualified
Moreover, there were extremely significant differences of measured indicators at tested concentrations, except CL at 50 μM, between the sample and model groups ( p < 0.001).
highly significantp < 0.0010.0× alphaqualifiedgold
Inferential Statistical Analysis The two-way ANOVA revealed a highly significant main effect of the dental product on antimicrobial activity (F (3, 352) = 185.42, p < 0.001), with a large effect size (partial η 2 = 0.61), indicating substantial differences in inhibition zone diameters among the tested formulations.