Barely Significant

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highly significantp < 0.0010.0× alphaqualifiedgold
The Phi PT between particular populations with K > 2 (chromosomes 1A, 4A, 5A, 2B, 3B, 2R, and 3R) was highly significant ( p < 0.001) and varied from 0.015 (between Pop2 and Pop3 for chromosome 3R) to 0.351 (between Pop2 and Pop3 for chromosome 2R) ( Table 4 ).
highly significantp = 0.0010.0× alphaqualifiedgold
The subsequent PERMANOVA confirmed very strong, highly significant metabolic shifts comparing predose and postdose metabolomics signatures with F = 20.665, R 2 = 0.408, p = 0.001 for visit 2 and with F = 16.084, R 2 = 0.349, p = 0.001 for visit 1, based on 999 permutations in both analysis cases.
extremely significantp < 0.0010.0× alphaqualified
highly significantp < 0.010.2× alphaqualifiedgold
For significance calculations, unpaired Student’s t -test (two sample, unequal variance) was used with the following significance designations: extremely significant ( p < 0.001), highly significant ( p < 0.01), significant ( p < 0.05); not significant ( p > 0.05). 5.
highly significantp < 0.0010.0× alphaqualifiedgold
The number of ICM cells was not different between the groups ( F 3,118 = 1.52, p = 0.21; Figure 8 A), but the difference in the TE cell number was highly significant ( F 3 ,118 = 5.85, p < 0.001; Figure 8 B), and subsequently, the ICM/TE ratio was significantly different between groups ( F 3,118 = 3.29, p = 0.023; Figure 8 C).
highly significantp < 0.0010.0× alphaqualifiedgold
There was a highly significant main effect of training day on both escape latency (F(3, 72) = 58.61, p < 0.001, η 2 p = 0.71; Greenhouse–Geisser corrected) and path length (F(3, 72) = 85.92, p < 0.001, η 2 p = 0.78; Figure 4 A,B), indicating that all groups, including the LPS-induced model group, acquired the task across the training period.