Optimization of acute medication use following eptinezumab initiation during a migraine attack: post hoc analysis of the RELIEF study.

Changes from baseline in HIT-6 total score did not show a clear trend of increasing improvement with poorer baseline optimization; however, eptinezumab treatment was associated with numerically larger improvements than placebo in HIT-6 total score at week 4, similar to the mTOQ-6 [ 16 ].

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