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Serotype and genotype distribution among invasive Streptococcus pneumoniae isolates in Colombia, 2005-2010.

PLoS One · 2014 · PMC3885649 · PMID 24416330

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an overall trendno p-value reported
However, the results may reflect an overall trend in the changes of S. pneumoniae in Colombia.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.