The In Vivo Antidiabetic Activity of Nigella sativa Is Mediated through Activation of the AMPK Pathway and Increased Muscle Glut4 Content.

Although the apparent NSE induced decrease in these parameters failed to reach statistical significance, such an action could participate in the improvement of systemic insulin sensitivity observed in our studies.

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At the end of four weeks of treatment, an increment of weight of about 6 to 10 g for each Meriones shawi group was observed, but no significant difference was apparent between them, albeit the weight gain of NSE-treated animals had a tendency to be lower. 3.2.

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