Double-blind comparison of iodamide and diatrizoate for excretory urography.

ne (0) 2 1 0 0 1 1 3 2 0 0 20 Dense (2) 5 0 13 9 15 11 9 4 15* 13 Faint (1) 9 16 5 8 2 6 8 12 3 2 None (0) 4 1 0 0 1 0 1 1 0 2 30 Dense (2) 4 2 13 10 16* 10 10 4 20 19 Faint (1) 15 20 10 12 7 13 12 18 2 4 None (0) 4 2 0 2 0 1 1 2 1 1 * = p <.05 ** = p <.01 Note: At all sites there is a definite trend toward denser opacification with iodamide than with Renografin.

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They found no correlation with sex or age of the patient. Other studies of iodamide have found a variable incidence of adverse reaction [4,5,6] but none of these represented a comparative trial with another agent. The data of our clinical trial indicates that the two agents are equal for parenchy- mal opacification but that iodamide is superior for opacifying the calices and pelvis. For the ureters and bladder, there is a clear trend towards superior performance by iodamide but not with the same degree of statistical confidence as was demonstrated for the calices and pelvis.

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