Understanding Anastomotic Healing in Colo-Rectal Surgery; a Multicentric 5-Year Analysis of Predictive Factors for Integrity and Fistula Formation.

Diagnostics (Basel) · 2026 · PMC13024959 · PMID 41897570

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did not reach statistical significancep ≈ 0.064so close (0.05 < p ≤ 0.1)

a positive trendno p-value reported

Neoadjuvant radiotherapy was also significantly associated with increased leakage risk (OR ≈ 3.29, 95% CI: 1.10–9.82, p ≈ 0.033), while neoadjuvant chemotherapy showed a positive trend toward higher leakage risk but did not reach statistical significance (OR ≈ 2.87, 95% CI: 0.94–8.78, p ≈ 0.064).

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