<i>Saussurea involucrata</i> Cultures for High-Altitude Illness: Enhancing Hypoxia Tolerance and Protecting Against Acute/Chronic Hypoxic Injury.

For lipid metabolism, no significant intergroup differences were found in total cholesterol and HDL-C, and triglyceride levels were significantly increased in the SICs-L and Diamox groups, also showing an increasing trend in the C-SICs-M group.

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However, it also induced fluctuations in some metabolic and organ function indicators, as well as exerting an adverse trend on behavioral performance related to spatial learning and memory.

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However, these differences did not reach statistical significance, which suggests that the improvement effect of SICs-M on chronic hypoxia-induced cognitive impairment is weak, due to a lack of strong evidence.

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The total distance traveled, total time, and escape latency of the SICs-M and Diamox groups showed a decreasing trend, indicating a tendency of cognitive improvement compared with the Model group.

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