Noninvasive Evaluation of Ventricular Filling Pressure and Pulmonary Vascular Reserve in Adults With Fontan Circulation.

Among those at low risk of PAWP elevation, exercise PVP indexed to peak V o 2 showed a trend for predicting exercise PVRI (β=0.32 WU·m 2 per mm Hg/100 mL per min [95% CI, 0.00–0.64]; P =0.06), whereas it was not in those at high risk (β=−0.43 WU·m 2 per mm Hg/100 mL per min [95% CI, −1.03 to 1.67]; P =0.13). ΔPVP with exercise indexed to peak V o 2 was also associated with ΔPVRI (β=0.91

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ΔPVP with exercise indexed to peak V o 2 was also associated with ΔPVRI (β=0.91 per mm Hg/100 mL per min [95% CI, 0.00–1.83]; P =0.05; Figure S2 ), and a positive trend was noted in those without an elevated PAWP (β=1.29 per mm Hg/100 mL per min [95% CI, −0.08 to 2.67]; P =0.06) but not in those with elevated PAWP (β=−0.38 per mm Hg/100 mL per min [95% CI, −1.76 to 0.99]; P =0.53).

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