Circulating tumor cells predict myeloma outcomes in patients treated with daratumumab, bortezomib, lenalidomide, and dexamethasone.

Blood · 2026 · PMC12883856 · PMID 41060326

Europe PMC DOI

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a favorable trendno p-value reported

A favorable trend toward improved PFS with D-VRd compared with VRd was also observed in CTC-high patients.

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a positive trendno p-value reported

D-VRd improved and sustained MRD-negativity rates in CTC-high and CTC-low, and improved PFS for CTC-low with a positive trend in CTC-high patients.

also in 11,005 other papers

did not reach statistical significanceno p-value reported

However, this did not reach statistical significance and would require longer follow-up for confirmation.

also in 111,027 other papers

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