Design, synthesis, and anticancer activity of novel isocryptolepine 'aza' type acyl thiourea derivatives via combined experimental and computational approach.

Biosci Rep · 2026 · PMC12863032 · PMID 41428767

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a clear trendno p-value reported

In the case of carbonic anhydrase, the inhibitory profile of these derivatives was superior to the standard oleanolic acid, with a clear trend favoring longer alkyl chains.

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