Uptake of DPYD and UGT1A1 testing in Italy and adherence to pharmacogenetic guidelines: A 5-year perspective from an EQA provider.

Br J Clin Pharmacol · 2026 · PMC12850544 · PMID 40905546

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an encouraging trendno p-value reported

It highlights an encouraging trend toward improved accuracy and guideline adherence, reflecting increasing awareness and harmonization in clinical pharmacogenetic practice.

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a clear trendno p-value reported

Regarding the accuracy of clinical interpretation stratified by the guideline referenced, there is a clear trend showing a decrease in clinical interpretation errors over the years, particularly for reports referencing the SIF‐AIOM guidelines, with errors decreasing to only 13% in 2023 (Figure 3D ). 3.6.

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