Investigation of antibiotic resistance against pathogens isolated from respiratory samples in intensive care units after SARS-CoV-2 pandemic.

Although not statistically significant, a decreasing trend in resistance to cephalosporins was observed in the post-pandemic period (cefazolin: 88.9% vs. 80.4%, p = 0.408; cefoxitin: 31.1% vs. 19.4%, p = 0.232; ceftazidime: 72.2% vs. 66.2%, p = 0.559; ceftriaxone: 81.6% vs. 66.2%, p = 0.101; cefepime: 64.8% vs. 57.4%, p = 0.489) (Table 5 ).

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97.7%, p = 0.079 respectively) was already high in the pre-pandemic period and showed further increases after the pandemic, these changes did not reach statistical significance (Table 2 ).

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Likewise, Klebsiella pneumoniae strains resistant to carbapenems have been reported to show an increasing trend since 2002, and this rise has accelerated during the pandemic, reaching resistance rates as high as 53% [ 2 ].

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