Similarly, Kaplan–Meier analysis showed a trend for earlier grade ≥ 3 corneal exam findings with higher belantamab mafodotin exposures, but stepwise Cox regression found no significant associations with time to these exam findings.
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Belantamab Mafodotin with Pomalidomide and Dexamethasone in Relapsed/Refractory Multiple Myeloma: A Comprehensive Exposure-Response Analysis of the DREAMM-8 Study.
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The sentences
There was a slight trend of decreasing probability as cys-mcMMAF exposures increased, but this did not meet significance criteria, nor did any covariate association.
While logistic regression showed patients with these events had slightly higher belantamab mafodotin exposures, and there was a small trend for decreasing probability of event with increasing cys-mcMMAF exposures, neither exposure metric was significant.