Real-World Effectiveness and Safety of Immune Checkpoint Inhibitors Combined with Chemotherapy in Taiwanese Patients with Extensive-Stage Small Cell Lung Cancer.

Among clinical variables, liver metastasis emerged as a significant negative prognostic factor (HR = 2.00, 95% CI: 1.21–3.30, p = 0.006), while other factors such as age, ECOG performance status, and brain or lung metastases did not reach statistical significance in the multivariate model. 3.5.

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In contrast, the Kaplan–Meier analysis of PFS showed no statistically significant difference across AE subgroups (log-rank p = 0.14), though a favorable trend was observed.

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