Excess Neonatal Testosterone Causes Male-Specific Social and Fear Memory Deficits in Wild-Type Mice.

A two-way ANOVA of the transformed PI in the choice phase uncovered no main effect of sex ( F (1,65) = 2.188; p = 0.144; η 2 = 0.028), a main effect of treatment ( F (1,65) = 5.743; p = 0.019; η 2 = 0.073), and a statistical trend of a sex × treatment interaction ( F (1,65) = 3.827; p = 0.055; η 2 = 0.049).

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A Tukey post hoc test indicated that females treated on PN0 with testosterone had significantly higher freezing than Males + Veh (p = 0.047) and Males + T (p = 0.0003), and a trend towards significance compared to Females + Veh (p = 0.073). *p<0.05, ***p<0.001, #p<0.10.

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