Evaluation of the Effects of the Sodium-Glucose Cotransporter 2 Inhibitors and Sacubitril/Valsartan Combined Therapy in Patients with HFrEF: An Echocardiographic Study.

Int J Mol Sci · 2025 · PMC12193552 · PMID 40565116

Europe PMC DOI

hedged sentence

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closest p

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boldest claim

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did not reach statistical significancep -value = 0.13not close (p > 0.1)

a possible trendno p-value reported

Although the difference did not reach statistical significance ( p -value = 0.13), it suggests a possible trend toward a greater biomarker response in patients who tolerated up-titration.

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