Validation of the CTS5 in four prospective, multicenter, randomized ABCSG trials.

Breast · 2025 · PMC11904565 · PMID 39985843

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did not reach statistical significanceno p-value reported

In the ABCSG-16 cohort, a notable benefit of extending ET was observed in the high-risk group, even though the result did not reach statistical significance.

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a numerical trendno p-value reported

The predictive performance of the continuous CTS5 could not be confirmed on the relative scale (interaction p-value 0.47), although there was a numerical trend favoring additional five years of ET in patients with higher CTS5 values.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.